Sterile formulations – Injectables, eye drops and eye ointments PDF Notes :- Click Now

Sterile formulations

Sterile dosage forms containing therapeutic agents do not present any viable microbes parenteral, opthalmic and irrigating preparations are the prime sterile dosage product among which the parenteral products are unique as they are injected in the internal body carities through the skin or mucous membranes.

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Sterile dosage forms are those which are free from any microorganisms, dust, fibres, and foreign particles, and should be isotonic.

Parenteral preparations as name suggests (par+enteral) are those which are administered other than enteral routes.

Injectables:

Injectables are used to relax facial wrinkles and folds (such as “smile lines”), contour the body (such as reducing the appearance of a “double chin”) and improve the signs of facial fat loss by creating structure, framework and volume to the face and lips.

Eye drops:

These are the aqueous or oily solution or suspension that are installed into the conjunctival sac of the eye.

These are used as anaesthetics, anti-inflammatory agents, antiseptics, diagnostic agent, mitotics, mydriatics and artificial tears.

Examples:

• Atropine sulphate eyedrops
• Physostigmine eyedrops
• Hyoscine eyedrops

Eye ointment:

• These are placed in the conjunctival sac or applied to the margins of the eyelids. Ointments are thicker than drops and that means they can stay in your eye longer.
• They are used when the medicine needs to work directly in your eye to relieve or treat eye conditions.

Eg: Bacitracin, ophthalmic ointment.