GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test Series 2

1 / 50

1. What is the advantage L-Dopa over dopamine?

2 / 50

2. With ferric chloride hydrolysable tannins produce

3 / 50

3. Arabin oxidase is present in one of the following carbohydrate:

4 / 50

4. Iaspgol seeds are adulterated with

5 / 50

5. Trgacanth contains _______ % of moisture content.

6 / 50

6. Carrageen an is a

7 / 50

7. _______is the Ca++ channel blocker

8 / 50

8. Caramel has ____________ as a chemical constituent.

9 / 50

9. The purgative property of myrobalan is due to presence of

10 / 50

10. Bahera belongs to __________ family.

11 / 50

11. Wheat is derived from

12 / 50

12. Barium chloride is used for the identification of
(a)  (b)
(c)  (d)

13 / 50

13. Galls are vegetable outgrowths formed on the twigs of

14 / 50

14. All of the following come under Leguminosae except

15 / 50

15. Ashoka bark contains

16 / 50

16. In which plant trichomes contain resin?

17 / 50

17. Myrrh is

18 / 50

18. Synonum of amla is

19 / 50

19. Chemically gums consist of

20 / 50

20. Calcium salt of acidic polysaccharides is present in

21 / 50

21. Guggulipid obtained from the commiphoramukul belongs to family

22 / 50

22. Acacia catechu belongs to family

23 / 50

23. Indian gum is obtained from

24 / 50

24. Gossypol, a compound that has received major attention as male contraceptive
(a) Is a hydroxylated bi naphthalene derivative found in cotton seed oil

(b) Is an aorizanol ester found in rice bran oil

(c) Exhibits toxicity such as hypokalemic-induced paralysis

(d) Acts as an androgen antagonist.

25 / 50

25. Potato starch contains ________________ % of ash value.

26 / 50

26. Condensed tannins

27 / 50

27. Commercially dextran is known as

28 / 50

28. Spearmint contains

29 / 50

29. Which functional group is transferred by coenzyme pyridoxal phosphate?

30 / 50

30. __________% of pectin is obtained from carrots.
(a) 10 (b) 10 to 12
(c) 10 to 15 (d) 5

31 / 50

31. One of the following is also known as Indian gooseberry:

32 / 50

32. Fiehe’s test is for

33 / 50

33. Gold beater’s skin test is used to detect the presence of

34 / 50

34. Triphlachurna contains

35 / 50

35. Tannins do not respond to

36 / 50

36. Hydrolysable tannins on hydrolysis by acid yields

37 / 50

37. Cymopsis tetragonolobus is a source for

38 / 50

38. Catechins and gallic acids are the examples of

39 / 50

39. Balsams are resinous substances which contain large proportions of

40 / 50

40. On melting double stranded DNA gives more number of?

41 / 50

41. Ferulic acid present in asafoetida on treatment with HCI produces

42 / 50

42. Gallic acid is an active chemical constituent of

43 / 50

43. The predominant chemical constituent of galls is

44 / 50

44. Behda consist of dried ripe fruits of Terminalia balerica, which belongs to family

45 / 50

45. Myroxylon balsmum is the official source of

46 / 50

46. Example of pseudo tannis type is

47 / 50

47. Colophony contains about 90% of

48 / 50

48. The algae Garcilaria contervoides is used for the preparation of

49 / 50

49. Gumghatti is classified as a

50 / 50

50. Black catechu gives _______ colour with FeCl3

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Which of the following drug belongs to 1st line

2 / 50

Saturated hydrocarbons are otherwise referred as............................

3 / 50

Which of the following is an active agent in antiseptic.

4 / 50

Which of these anti-tubercular drugs are also active against leprosy

5 / 50

The heterocyclic nucleus present in sulphadiazine is

6 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

7 / 50

Which of the following drug belongs to sulfone group

8 / 50

Disinfectants are _______

9 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

10 / 50

Which of the following is commonly used in treatment of acne

11 / 50

Septran is a trade name for

12 / 50

Name of drug containing dianilino group........

13 / 50

Antiseptic have lower bacterial resistance

14 / 50

Mechanism of sulfonamides antibacterial effect is

15 / 50

DDS stands for......

16 / 50

Select an anti-leprotic drug among the given...........

17 / 50

Name the drug containing pyrazine ring.........

18 / 50

Antiseptic are

19 / 50

Storage condition for Rifampicin is...............

20 / 50

Which of the following metal ion shows antimicrobial action.

21 / 50

Vitamin B6 is administered along with INH to avoid....................

22 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

23 / 50

Which of the given is not ant amoebic drug

24 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

25 / 50

Sulfonamides are mainly used in treatment of eye infection is

26 / 50

Triple bond with two carbon atoms on either side is called_______

27 / 50

Which of the following is not susceptible to alcohol compounds.

28 / 50

IUPAC name of INH is ...

29 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

30 / 50

Excystation is _______

31 / 50

Dapsone is use in combination with...........

32 / 50

Heterocyclic ring present in INH...................

33 / 50

Protozoan parasite responsible for amebiasis is ________

34 / 50

The C=C bond in the chain of the compound considered is shown by________

35 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

36 / 50

Transmission of amoebiasis occur through_________

37 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

38 / 50

Functional group present in INH

39 / 50

Given the following are long acting sulphonamides except.

40 / 50

Major side effects of INH.....

41 / 50

Sulfonamides are....................... in action.

42 / 50

Functional group present in dapsone is ............

43 / 50

Leprosy is also known as.........

44 / 50

Amobiasis is also known as.........................

45 / 50

Extra intestinal infections include

46 / 50

Dienes are the name given to compounds with_______

47 / 50

The substituent groups that are commonly associated with benzene are______

48 / 50

IUPAC name of Dapsone is .......................

49 / 50

Mechanism by which the antiseptic shows their action

50 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

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The average score is 23%

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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

2 / 50

Morphine affects the eyes by:

3 / 50

Muscarinic receptor M4 are mainly located at

4 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

5 / 50

Hormones that increase cyclic AMP in the larger organ include all except

6 / 50

Epinephrine is added to local anaesthetics

7 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

8 / 50

Drug having high affinity but low intrinsic activity is called

9 / 50

All of the following may enhance the action of sulfonylureas except

10 / 50

Action of D-tubocurarine is

11 / 50

Most of the drug is absorbed through

12 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

13 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

14 / 50

Undesirable effects of oral contraceptives include all except

15 / 50

Ganglionic blocking agent may cause all of the following except

16 / 50

Darifenacin is a

17 / 50

Which of the following is CYP450 enzyme inhibitor?

18 / 50

Atropine blocks the muscarinic actions of acetylcholine by

19 / 50

Beta agonist used in bronchial asthma exert action by

20 / 50

Drug of choice in motion sickness is

21 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

22 / 50

Antidote of organo phosphorus poisoning is

23 / 50

In belladonna poisoning convulsions can be controlled by

24 / 50

Atropine over Dosage may cause all of the following except

25 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

26 / 50

Neostigmine may cause all of the following except

27 / 50

Sweating is inhibited by

28 / 50

In the bioassay the conviction activity in mice is observed during……………use.

29 / 50

Local anesthetics produce:

30 / 50

Serious unwanted effect of epinephrine is

31 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

32 / 50

Drug of choice in the treatment of cardiogenic shock is

33 / 50

Which of the following a is directly acting sympathomimetic agent?

34 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

35 / 50

Pilocarpine is classified as

36 / 50

Phentolamine is competitive antagonism of

37 / 50

Major adverse effect of clonidine is

38 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

39 / 50

Antidote of atropine is

40 / 50

Isolated rabbit jejunum is used

41 / 50

Alcuronium is a semisynthetic derivative with similar properties of

42 / 50

Which of the following receptor shows the slowest response?

43 / 50

Spironolactone is a prodrug and its active metabolite is

44 / 50

All of the following statement related to neostigmine are correct except

45 / 50

Mechanism of action of organic phosphate parathion is

46 / 50

………………drug having highest volume of distribution.

47 / 50

Tolbutamide is contraindicated in

48 / 50

Most common Phase -2nd reaction is

49 / 50

Bioassays are carried out to:

50 / 50

In urinary incontinence following drug is widely used:

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The average score is 30%

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GPAT Mock Test-2024

1 / 100

Aminotransferases usually requires the following for their activity:

2 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

3 / 100

At physiological pH, the following compound would be mostly in the

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4 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

5 / 100

One of the following statements is not true:

6 / 100

Identify the one rational combination which has clinical benefit:

7 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

8 / 100

Aliskiren acts by

9 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

10 / 100

Triterpenoids are active constituents of

11 / 100

The applicability of Noyes-Whitney equation is to describe

12 / 100

Eugenol is present in

13 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

14 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

15 / 100

Drugs in suspensions and semi-solid formulations always degrade by

16 / 100

Tropane alkaloids are not present in

17 / 100

Digitalis toxicity is enhanced by co-administration of

18 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

19 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

20 / 100

Nicotinic action of acetylcholine is blocked by the drug

21 / 100

Alkaloids are not precipitated by

22 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

23 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

24 / 100

The characteristic of non-linear pharmacokinetics includes:

25 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

26 / 100

Sildenafil is used for treatment of one of the following
disorders:

27 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

28 / 100

Which one of the following statements is wrong?

29 / 100

The following protein/polypeptide has a quaternary structure:

30 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

31 / 100

Coulter counter is used in determination of

32 / 100

The chemical behaviour of morphine alkaloid is

33 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

34 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

35 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

36 / 100

The healing agent used in hand creams is

37 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

38 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

39 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

40 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

41 / 100

For glyburide, all of the following metabolic reactions are logical except:

42 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

43 / 100

Which one of the following is a plasminogen activator?

44 / 100

Amitryptyline is synthesized from the following starting material:

45 / 100

Class 100 area is referred to

46 / 100

Cyclophosphamide as anticancer agent acts as

47 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

48 / 100

Geriatric population should be included in the following phase of clinical trials:

49 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

50 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

51 / 100

Measurement of inulin renal clearance is a measure for

52 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

53 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

54 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

55 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

56 / 100

The given antibiotic is an example of ansamycins:

57 / 100

Oxidative phosphorylation involves

58 / 100

Ganciclovir is mainly used for the treatment of infection caused by

59 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

60 / 100

Choose the right combination:

61 / 100

The role of borax in cold creams is

62 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

63 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

64 / 100

The amount of barbaloin present in Aloe vera is

65 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

66 / 100

An isosteric replacement for carboxylic acid group is

67 / 100

In which of the following techniques, the sample is kept below triple point?

68 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

69 / 100

Artemisinin contains the following group in its structure:

70 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

71 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

72 / 100

X-ray crystallographic analysis of an optically active compound determines its

73 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

74 / 100

Gingkgo biloba is used for its

75 / 100

The temperature condition for storage of drug products under cold temperature is given as

76 / 100

Bacopa monnieri plant belongs to the family

77 / 100

The ability of human eye using illuminated area to detect a particle is limited to

78 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

79 / 100

Which one of the following drugs is not a typical antipsychotic agent?

80 / 100

Anisocytic stomata are present in

81 / 100

Selective serotonin reuptake inhibitor is

82 / 100

In nail polish, the following polymer is used as a film-former:

83 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

84 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

85 / 100

Which one of the following statements is wrong?

86 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

87 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

88 / 100

An example of N-glycoside is

89 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

90 / 100

Ethambutol molecule has

91 / 100

Humectants added in cosmetic preparations generally act by

92 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

93 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

94 / 100

Drugs following one compartment open model pharmacokinetics eliminate

95 / 100

In thiazides, following substituent is essential for diuretic activity:

96 / 100

Quassia wood is adulterated with

97 / 100

Rabies vaccine (living) is prepared using

98 / 100

Which of the following non-opioid analgesics is a prodrug?

99 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

100 / 100

Guggul lipids are obtained from

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The average score is 20%

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Pharmacology MCQs for DPEE and GPAT

1 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

2 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

3 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

4 / 51

An antagonist is a substance that:

5 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

6 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

7 / 51

Indicate the location of M2 cholinoreceptor type:

8 / 51

Parasympathomimetic drugs cause:

9 / 51

Local anesthetics produce:

10 / 51

Acetylcholine is not a specific neurotransmitter at:

11 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

12 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

13 / 51

Pick out the answer which is the most appropriate to the term “receptor”

14 / 51

What does “affinity” mean?

15 / 51

Pharmacokinetics is:

 

16 / 51

Target proteins which a drug molecule binds are:

17 / 51

An agonist is a substance that:

18 / 51

Pharmacodynamics involves the following?

19 / 51

Pharmacodynamics involves the study of following EXCEPT:

20 / 51

What kind of substances can’t permeate membranes by passive diffusion?

21 / 51

What is implied by «active transport»?

22 / 51

What does “pharmacokinetics” include?

23 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

24 / 51

A good local anesthetic agent shouldn’t cause:

25 / 51

The group of nicotinic receptor-blocking drugs consists of:

26 / 51

A hydrophilic medicinal agent has the following property:

27 / 51

Pharmacodynamics involves the study of following?

28 / 51

Indicate a muscarinic receptor-blocking drug:

29 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

30 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

31 / 51

The main mechanism of most drugs absorption in GI tract is:

32 / 51

Most local anesthetic agents consist of:

33 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

34 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

35 / 51

Which of the following agents is a ganglion-blocking drug?

36 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

37 / 51

What does “pharmacokinetics” include?

38 / 51

The mechanism of atropine action is:

39 / 51

Characteristics of carbachol include all of the following EXCEPT:

40 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

41 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

42 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

43 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

44 / 51

The reasons determing bioavailability are:

45 / 51

What does the term “bioavailability” mean?

46 / 51

Acetylcholine is not used in clinical practice because:

47 / 51

Muscarinic receptors are located in:

48 / 51

M3 receptor subtype is located:

49 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

50 / 51

Ionizable group is responsible for:

51 / 51

What does “pharmacokinetics” include?

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