GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test Series 2

1 / 50

1. What is the advantage L-Dopa over dopamine?

2 / 50

2. Potato starch contains ________________ % of ash value.

3 / 50

3. Gallic acid is an active chemical constituent of

4 / 50

4. Triphlachurna contains

5 / 50

5. Fiehe’s test is for

6 / 50

6. Galls are vegetable outgrowths formed on the twigs of

7 / 50

7. Gold beater’s skin test is used to detect the presence of

8 / 50

8. Barium chloride is used for the identification of
(a)  (b)
(c)  (d)

9 / 50

9. Myroxylon balsmum is the official source of

10 / 50

10. Catechins and gallic acids are the examples of

11 / 50

11. Ferulic acid present in asafoetida on treatment with HCI produces

12 / 50

12. Gossypol, a compound that has received major attention as male contraceptive
(a) Is a hydroxylated bi naphthalene derivative found in cotton seed oil

(b) Is an aorizanol ester found in rice bran oil

(c) Exhibits toxicity such as hypokalemic-induced paralysis

(d) Acts as an androgen antagonist.

13 / 50

13. Colophony contains about 90% of

14 / 50

14. The purgative property of myrobalan is due to presence of

15 / 50

15. The predominant chemical constituent of galls is

16 / 50

16. The algae Garcilaria contervoides is used for the preparation of

17 / 50

17. Black catechu gives _______ colour with FeCl3

18 / 50

18. All of the following come under Leguminosae except

19 / 50

19. Myrrh is

20 / 50

20. Tannins do not respond to

21 / 50

21. Acacia catechu belongs to family

22 / 50

22. Arabin oxidase is present in one of the following carbohydrate:

23 / 50

23. Indian gum is obtained from

24 / 50

24. Example of pseudo tannis type is

25 / 50

25. On melting double stranded DNA gives more number of?

26 / 50

26. Which functional group is transferred by coenzyme pyridoxal phosphate?

27 / 50

27. Hydrolysable tannins on hydrolysis by acid yields

28 / 50

28. Wheat is derived from

29 / 50

29. _______is the Ca++ channel blocker

30 / 50

30. Commercially dextran is known as

31 / 50

31. With ferric chloride hydrolysable tannins produce

32 / 50

32. Trgacanth contains _______ % of moisture content.

33 / 50

33. __________% of pectin is obtained from carrots.
(a) 10 (b) 10 to 12
(c) 10 to 15 (d) 5

34 / 50

34. Condensed tannins

35 / 50

35. Ashoka bark contains

36 / 50

36. Carrageen an is a

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37. Balsams are resinous substances which contain large proportions of

38 / 50

38. Calcium salt of acidic polysaccharides is present in

39 / 50

39. Guggulipid obtained from the commiphoramukul belongs to family

40 / 50

40. Bahera belongs to __________ family.

41 / 50

41. One of the following is also known as Indian gooseberry:

42 / 50

42. Spearmint contains

43 / 50

43. Synonum of amla is

44 / 50

44. Cymopsis tetragonolobus is a source for

45 / 50

45. Chemically gums consist of

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46. Iaspgol seeds are adulterated with

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47. Gumghatti is classified as a

48 / 50

48. Caramel has ____________ as a chemical constituent.

49 / 50

49. In which plant trichomes contain resin?

50 / 50

50. Behda consist of dried ripe fruits of Terminalia balerica, which belongs to family

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Sulfonamides are mainly used in treatment of eye infection is

2 / 50

The C=C bond in the chain of the compound considered is shown by________

3 / 50

Excystation is _______

4 / 50

Given the following are long acting sulphonamides except.

5 / 50

Transmission of amoebiasis occur through_________

6 / 50

Which of the following drug belongs to 1st line

7 / 50

Functional group present in INH

8 / 50

Heterocyclic ring present in INH...................

9 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

10 / 50

Name the drug containing pyrazine ring.........

11 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

12 / 50

Name of drug containing dianilino group........

13 / 50

Leprosy is also known as.........

14 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

15 / 50

Which of the following is an active agent in antiseptic.

16 / 50

Disinfectants are _______

17 / 50

Which of the following metal ion shows antimicrobial action.

18 / 50

Major side effects of INH.....

19 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

20 / 50

Protozoan parasite responsible for amebiasis is ________

21 / 50

Mechanism by which the antiseptic shows their action

22 / 50

DDS stands for......

23 / 50

Sulfonamides are....................... in action.

24 / 50

Antiseptic are

25 / 50

Which of the given is not ant amoebic drug

26 / 50

Dienes are the name given to compounds with_______

27 / 50

Septran is a trade name for

28 / 50

Triple bond with two carbon atoms on either side is called_______

29 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

30 / 50

The substituent groups that are commonly associated with benzene are______

31 / 50

Which of the following is not susceptible to alcohol compounds.

32 / 50

Amobiasis is also known as.........................

33 / 50

Which of the following drug belongs to sulfone group

34 / 50

Vitamin B6 is administered along with INH to avoid....................

35 / 50

IUPAC name of Dapsone is .......................

36 / 50

Antiseptic have lower bacterial resistance

37 / 50

Extra intestinal infections include

38 / 50

Mechanism of sulfonamides antibacterial effect is

39 / 50

Select an anti-leprotic drug among the given...........

40 / 50

Functional group present in dapsone is ............

41 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

42 / 50

IUPAC name of INH is ...

43 / 50

Dapsone is use in combination with...........

44 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

45 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

46 / 50

Saturated hydrocarbons are otherwise referred as............................

47 / 50

The heterocyclic nucleus present in sulphadiazine is

48 / 50

Which of these anti-tubercular drugs are also active against leprosy

49 / 50

Storage condition for Rifampicin is...............

50 / 50

Which of the following is commonly used in treatment of acne

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The average score is 21%

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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Phentolamine is competitive antagonism of

2 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

3 / 50

Morphine affects the eyes by:

4 / 50

Epinephrine is added to local anaesthetics

5 / 50

Which of the following a is directly acting sympathomimetic agent?

6 / 50

Neostigmine may cause all of the following except

7 / 50

………………drug having highest volume of distribution.

8 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

9 / 50

In urinary incontinence following drug is widely used:

10 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

11 / 50

Ganglionic blocking agent may cause all of the following except

12 / 50

Drug having high affinity but low intrinsic activity is called

13 / 50

Drug of choice in the treatment of cardiogenic shock is

14 / 50

Antidote of atropine is

15 / 50

Sweating is inhibited by

16 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

17 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

18 / 50

Darifenacin is a

19 / 50

Drug of choice in motion sickness is

20 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

21 / 50

All of the following statement related to neostigmine are correct except

22 / 50

Tolbutamide is contraindicated in

23 / 50

Serious unwanted effect of epinephrine is

24 / 50

In belladonna poisoning convulsions can be controlled by

25 / 50

Antidote of organo phosphorus poisoning is

26 / 50

Atropine blocks the muscarinic actions of acetylcholine by

27 / 50

Mechanism of action of organic phosphate parathion is

28 / 50

Alcuronium is a semisynthetic derivative with similar properties of

29 / 50

Beta agonist used in bronchial asthma exert action by

30 / 50

Local anesthetics produce:

31 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

32 / 50

Hormones that increase cyclic AMP in the larger organ include all except

33 / 50

Isolated rabbit jejunum is used

34 / 50

Most common Phase -2nd reaction is

35 / 50

Bioassays are carried out to:

36 / 50

Which of the following is CYP450 enzyme inhibitor?

37 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

38 / 50

Spironolactone is a prodrug and its active metabolite is

39 / 50

All of the following may enhance the action of sulfonylureas except

40 / 50

In the bioassay the conviction activity in mice is observed during……………use.

41 / 50

Atropine over Dosage may cause all of the following except

42 / 50

Which of the following receptor shows the slowest response?

43 / 50

Pilocarpine is classified as

44 / 50

Muscarinic receptor M4 are mainly located at

45 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

46 / 50

Undesirable effects of oral contraceptives include all except

47 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

48 / 50

Major adverse effect of clonidine is

49 / 50

Most of the drug is absorbed through

50 / 50

Action of D-tubocurarine is

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GPAT Mock Test-2024

1 / 100

In nail polish, the following polymer is used as a film-former:

2 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

3 / 100

An isosteric replacement for carboxylic acid group is

4 / 100

Aminotransferases usually requires the following for their activity:

5 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

6 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

7 / 100

Which one of the following statements is wrong?

8 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

9 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

10 / 100

Tropane alkaloids are not present in

11 / 100

Humectants added in cosmetic preparations generally act by

12 / 100

The chemical behaviour of morphine alkaloid is

13 / 100

Triterpenoids are active constituents of

14 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

15 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

16 / 100

In which of the following techniques, the sample is kept below triple point?

17 / 100

Anisocytic stomata are present in

18 / 100

Which one of the following drugs is not a typical antipsychotic agent?

19 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

20 / 100

Choose the right combination:

21 / 100

Ethambutol molecule has

22 / 100

Guggul lipids are obtained from

23 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

24 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

25 / 100

Drugs following one compartment open model pharmacokinetics eliminate

26 / 100

The characteristic of non-linear pharmacokinetics includes:

27 / 100

In thiazides, following substituent is essential for diuretic activity:

28 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

29 / 100

Geriatric population should be included in the following phase of clinical trials:

30 / 100

Which of the following non-opioid analgesics is a prodrug?

31 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

32 / 100

Artemisinin contains the following group in its structure:

33 / 100

Eugenol is present in

34 / 100

The given antibiotic is an example of ansamycins:

35 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

36 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

37 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

38 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

39 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

40 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

41 / 100

An example of N-glycoside is

42 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

43 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

44 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

45 / 100

Gingkgo biloba is used for its

46 / 100

Drugs in suspensions and semi-solid formulations always degrade by

47 / 100

Digitalis toxicity is enhanced by co-administration of

48 / 100

Sildenafil is used for treatment of one of the following
disorders:

49 / 100

The healing agent used in hand creams is

50 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

51 / 100

Selective serotonin reuptake inhibitor is

52 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

53 / 100

The temperature condition for storage of drug products under cold temperature is given as

54 / 100

For glyburide, all of the following metabolic reactions are logical except:

55 / 100

Class 100 area is referred to

56 / 100

The applicability of Noyes-Whitney equation is to describe

57 / 100

One of the following statements is not true:

58 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

59 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

60 / 100

The following protein/polypeptide has a quaternary structure:

61 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

62 / 100

The ability of human eye using illuminated area to detect a particle is limited to

63 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

64 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

65 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

66 / 100

Nicotinic action of acetylcholine is blocked by the drug

67 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

68 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

69 / 100

Ganciclovir is mainly used for the treatment of infection caused by

70 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

71 / 100

At physiological pH, the following compound would be mostly in the

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72 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

73 / 100

Which one of the following statements is wrong?

74 / 100

Which one of the following is a plasminogen activator?

75 / 100

Rabies vaccine (living) is prepared using

76 / 100

Measurement of inulin renal clearance is a measure for

77 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

78 / 100

Quassia wood is adulterated with

79 / 100

Aliskiren acts by

80 / 100

Cyclophosphamide as anticancer agent acts as

81 / 100

Amitryptyline is synthesized from the following starting material:

82 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

83 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

84 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

85 / 100

X-ray crystallographic analysis of an optically active compound determines its

86 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

87 / 100

Identify the one rational combination which has clinical benefit:

88 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

89 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

90 / 100

Alkaloids are not precipitated by

91 / 100

Bacopa monnieri plant belongs to the family

92 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

93 / 100

The role of borax in cold creams is

94 / 100

Oxidative phosphorylation involves

95 / 100

Coulter counter is used in determination of

96 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

97 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

98 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

99 / 100

The amount of barbaloin present in Aloe vera is

100 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

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Pharmacology MCQs for DPEE and GPAT

1 / 51

The reasons determing bioavailability are:

2 / 51

What does “pharmacokinetics” include?

3 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

4 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

5 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

6 / 51

The group of nicotinic receptor-blocking drugs consists of:

7 / 51

Pharmacodynamics involves the following?

8 / 51

An antagonist is a substance that:

9 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

10 / 51

What does “pharmacokinetics” include?

11 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

12 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

13 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

14 / 51

Pharmacokinetics is:

 

15 / 51

The main mechanism of most drugs absorption in GI tract is:

16 / 51

What kind of substances can’t permeate membranes by passive diffusion?

17 / 51

What is implied by «active transport»?