GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test Series 2

1 / 50

Spearmint contains

2 / 50

The algae Garcilaria contervoides is used for the preparation of

3 / 50

Gossypol, a compound that has received major attention as male contraceptive
(a) Is a hydroxylated bi naphthalene derivative found in cotton seed oil

(b) Is an aorizanol ester found in rice bran oil

(c) Exhibits toxicity such as hypokalemic-induced paralysis

(d) Acts as an androgen antagonist.

4 / 50

Myroxylon balsmum is the official source of

5 / 50

Gallic acid is an active chemical constituent of

6 / 50

Which functional group is transferred by coenzyme pyridoxal phosphate?

7 / 50

Ferulic acid present in asafoetida on treatment with HCI produces

8 / 50

Wheat is derived from

9 / 50

Trgacanth contains _______ % of moisture content.

10 / 50

In which plant trichomes contain resin?

11 / 50

Commercially dextran is known as

12 / 50

Example of pseudo tannis type is

13 / 50

Black catechu gives _______ colour with FeCl3

14 / 50

Triphlachurna contains

15 / 50

Barium chloride is used for the identification of
(a)  (b)
(c)  (d)

16 / 50

Myrrh is

17 / 50

Behda consist of dried ripe fruits of Terminalia balerica, which belongs to family

18 / 50

The purgative property of myrobalan is due to presence of

19 / 50

Carrageen an is a

20 / 50

Acacia catechu belongs to family

21 / 50

What is the advantage L-Dopa over dopamine?

22 / 50

Calcium salt of acidic polysaccharides is present in

23 / 50

Galls are vegetable outgrowths formed on the twigs of

24 / 50

The predominant chemical constituent of galls is

25 / 50

__________% of pectin is obtained from carrots.
(a) 10 (b) 10 to 12
(c) 10 to 15 (d) 5

26 / 50

Chemically gums consist of

27 / 50

Ashoka bark contains

28 / 50

Balsams are resinous substances which contain large proportions of

29 / 50

Arabin oxidase is present in one of the following carbohydrate:

30 / 50

Gold beater’s skin test is used to detect the presence of

31 / 50

Hydrolysable tannins on hydrolysis by acid yields

32 / 50

Cymopsis tetragonolobus is a source for

33 / 50

Colophony contains about 90% of

34 / 50

Potato starch contains ________________ % of ash value.

35 / 50

Indian gum is obtained from

36 / 50

Synonum of amla is

37 / 50

Guggulipid obtained from the commiphoramukul belongs to family

38 / 50

On melting double stranded DNA gives more number of?

39 / 50

With ferric chloride hydrolysable tannins produce

40 / 50

Caramel has ____________ as a chemical constituent.

41 / 50

Iaspgol seeds are adulterated with

42 / 50

Tannins do not respond to

43 / 50

Gumghatti is classified as a

44 / 50

Catechins and gallic acids are the examples of

45 / 50

Bahera belongs to __________ family.

46 / 50

Condensed tannins

47 / 50

One of the following is also known as Indian gooseberry:

48 / 50

_______is the Ca++ channel blocker

49 / 50

Fiehe’s test is for

50 / 50

All of the following come under Leguminosae except

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The average score is 25%

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Which of the following drug belongs to 1st line

2 / 50

Mechanism of sulfonamides antibacterial effect is

3 / 50

Storage condition for Rifampicin is...............

4 / 50

Which of the following is not susceptible to alcohol compounds.

5 / 50

Protozoan parasite responsible for amebiasis is ________

6 / 50

Septran is a trade name for

7 / 50

Functional group present in INH

8 / 50

Excystation is _______

9 / 50

Antiseptic are

10 / 50

Sulfonamides are mainly used in treatment of eye infection is

11 / 50

Heterocyclic ring present in INH...................

12 / 50

The heterocyclic nucleus present in sulphadiazine is

13 / 50

Given the following are long acting sulphonamides except.

14 / 50

Which of these anti-tubercular drugs are also active against leprosy

15 / 50

Antiseptic have lower bacterial resistance

16 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

17 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

18 / 50

Mechanism by which the antiseptic shows their action

19 / 50

Which of the following metal ion shows antimicrobial action.

20 / 50

Major side effects of INH.....

21 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

22 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

23 / 50

Extra intestinal infections include

24 / 50

Which of the following is an active agent in antiseptic.

25 / 50

Vitamin B6 is administered along with INH to avoid....................

26 / 50

Which of the following is commonly used in treatment of acne

27 / 50

Triple bond with two carbon atoms on either side is called_______

28 / 50

Functional group present in dapsone is ............

29 / 50

The C=C bond in the chain of the compound considered is shown by________

30 / 50

Sulfonamides are....................... in action.

31 / 50

IUPAC name of INH is ...

32 / 50

Name of drug containing dianilino group........

33 / 50

Which of the given is not ant amoebic drug

34 / 50

Dapsone is use in combination with...........

35 / 50

Transmission of amoebiasis occur through_________

36 / 50

Select an anti-leprotic drug among the given...........

37 / 50

Leprosy is also known as.........

38 / 50

Which of the following drug belongs to sulfone group

39 / 50

Amobiasis is also known as.........................

40 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

41 / 50

Disinfectants are _______

42 / 50

Name the drug containing pyrazine ring.........

43 / 50

DDS stands for......

44 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

45 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

46 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

47 / 50

Saturated hydrocarbons are otherwise referred as............................

48 / 50

Dienes are the name given to compounds with_______

49 / 50

The substituent groups that are commonly associated with benzene are______

50 / 50

IUPAC name of Dapsone is .......................

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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

2 / 50

Atropine blocks the muscarinic actions of acetylcholine by

3 / 50

All of the following may enhance the action of sulfonylureas except

4 / 50

Drug of choice in motion sickness is

5 / 50

Antidote of organo phosphorus poisoning is

6 / 50

Which of the following is CYP450 enzyme inhibitor?

7 / 50

Tolbutamide is contraindicated in

8 / 50

Neostigmine may cause all of the following except

9 / 50

Most common Phase -2nd reaction is

10 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

11 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

12 / 50

Mechanism of action of organic phosphate parathion is

13 / 50

Morphine affects the eyes by:

14 / 50

Serious unwanted effect of epinephrine is

15 / 50

Which of the following receptor shows the slowest response?

16 / 50

Phentolamine is competitive antagonism of

17 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

18 / 50

Local anesthetics produce:

19 / 50

In belladonna poisoning convulsions can be controlled by

20 / 50

Darifenacin is a

21 / 50

Epinephrine is added to local anaesthetics

22 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

23 / 50

Spironolactone is a prodrug and its active metabolite is

24 / 50

Undesirable effects of oral contraceptives include all except

25 / 50

Major adverse effect of clonidine is

26 / 50

Hormones that increase cyclic AMP in the larger organ include all except

27 / 50

In urinary incontinence following drug is widely used:

28 / 50

Which of the following a is directly acting sympathomimetic agent?

29 / 50

Atropine over Dosage may cause all of the following except

30 / 50

Alcuronium is a semisynthetic derivative with similar properties of

31 / 50

Most of the drug is absorbed through

32 / 50

Action of D-tubocurarine is

33 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

34 / 50

………………drug having highest volume of distribution.

35 / 50

Isolated rabbit jejunum is used

36 / 50

Pilocarpine is classified as

37 / 50

Sweating is inhibited by

38 / 50

Ganglionic blocking agent may cause all of the following except

39 / 50

Drug having high affinity but low intrinsic activity is called

40 / 50

Bioassays are carried out to:

41 / 50

Muscarinic receptor M4 are mainly located at

42 / 50

Beta agonist used in bronchial asthma exert action by

43 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

44 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

45 / 50

Antidote of atropine is

46 / 50

In the bioassay the conviction activity in mice is observed during……………use.

47 / 50

All of the following statement related to neostigmine are correct except

48 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

49 / 50

Drug of choice in the treatment of cardiogenic shock is

50 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

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The average score is 30%

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GPAT Mock Test-2024

1 / 100

An isosteric replacement for carboxylic acid group is

2 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

3 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

4 / 100

Artemisinin contains the following group in its structure:

5 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

6 / 100

Which one of the following is a plasminogen activator?

7 / 100

In which of the following techniques, the sample is kept below triple point?

8 / 100

Eugenol is present in

9 / 100

Drugs in suspensions and semi-solid formulations always degrade by

10 / 100

The chemical behaviour of morphine alkaloid is

11 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

12 / 100

Coulter counter is used in determination of

13 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

14 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

15 / 100

The given antibiotic is an example of ansamycins:

16 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

17 / 100

Aminotransferases usually requires the following for their activity:

18 / 100

Which one of the following statements is wrong?

19 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

20 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

21 / 100

Which one of the following statements is wrong?

22 / 100

An example of N-glycoside is

23 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

24 / 100

Tropane alkaloids are not present in

25 / 100

Guggul lipids are obtained from

26 / 100

The temperature condition for storage of drug products under cold temperature is given as

27 / 100

The characteristic of non-linear pharmacokinetics includes:

28 / 100

Gingkgo biloba is used for its

29 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

30 / 100

Humectants added in cosmetic preparations generally act by

31 / 100

Amitryptyline is synthesized from the following starting material:

32 / 100

Drugs following one compartment open model pharmacokinetics eliminate

33 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

34 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

35 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

36 / 100

Choose the right combination:

37 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

38 / 100

The amount of barbaloin present in Aloe vera is

39 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

40 / 100

The applicability of Noyes-Whitney equation is to describe

41 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

42 / 100

Sildenafil is used for treatment of one of the following
disorders:

43 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

44 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

45 / 100

In thiazides, following substituent is essential for diuretic activity:

46 / 100

Triterpenoids are active constituents of

47 / 100

Nicotinic action of acetylcholine is blocked by the drug

48 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

49 / 100

In nail polish, the following polymer is used as a film-former:

50 / 100

Geriatric population should be included in the following phase of clinical trials:

51 / 100

Which one of the following drugs is not a typical antipsychotic agent?

52 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

53 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

54 / 100

The role of borax in cold creams is

55 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

56 / 100

Oxidative phosphorylation involves

57 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

58 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

59 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

60 / 100

Cyclophosphamide as anticancer agent acts as

61 / 100

For glyburide, all of the following metabolic reactions are logical except:

62 / 100

Bacopa monnieri plant belongs to the family

63 / 100

Identify the one rational combination which has clinical benefit:

64 / 100

Quassia wood is adulterated with

65 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

66 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

67 / 100

One of the following statements is not true:

68 / 100

Alkaloids are not precipitated by

69 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

70 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

71 / 100

Which of the following non-opioid analgesics is a prodrug?

72 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

73 / 100

Ganciclovir is mainly used for the treatment of infection caused by

74 / 100

Aliskiren acts by

75 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

76 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

77 / 100

Ethambutol molecule has

78 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

79 / 100

Digitalis toxicity is enhanced by co-administration of

80 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

81 / 100

Class 100 area is referred to

82 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

83 / 100

Measurement of inulin renal clearance is a measure for

84 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

85 / 100

Rabies vaccine (living) is prepared using

86 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

87 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

88 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

89 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

90 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

91 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

92 / 100

The healing agent used in hand creams is

93 / 100

Selective serotonin reuptake inhibitor is

94 / 100

The following protein/polypeptide has a quaternary structure:

95 / 100

X-ray crystallographic analysis of an optically active compound determines its

96 / 100

Anisocytic stomata are present in

97 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

98 / 100

The ability of human eye using illuminated area to detect a particle is limited to

99 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

100 / 100

At physiological pH, the following compound would be mostly in the

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Pharmacology MCQs for DPEE and GPAT

1 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

2 / 51

Muscarinic receptors are located in:

3 / 51

Characteristics of carbachol include all of the following EXCEPT:

4 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

5 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

6 / 51

M3 receptor subtype is located:

7 / 51

Ionizable group is responsible for:

8 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

9 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

10 / 51

Pharmacodynamics involves the study of following EXCEPT:

11 / 51

The mechanism of atropine action is:

12 / 51

What does “pharmacokinetics” include?

13 / 51

Which of the following agents is a ganglion-blocking drug?

14 / 51

Local anesthetics produce:

15 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

16 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

17 / 51

Parasympathomimetic drugs cause:

18 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

19 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

20 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

21 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

22 / 51

What kind of substances can’t permeate membranes by passive diffusion?

23 / 51

The main mechanism of most drugs absorption in GI tract is:

24 / 51

Acetylcholine is not used in clinical practice because:

25 / 51

What does “affinity” mean?

26 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

27 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

28 / 51

Target proteins which a drug molecule binds are:

29 / 51

Indicate a muscarinic receptor-blocking drug:

30 / 51

A hydrophilic medicinal agent has the following property:

31 / 51

What does “pharmacokinetics” include?

32 / 51

The reasons determing bioavailability are:

33 / 51

What does the term “bioavailability” mean?

34 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

35 / 51

What is implied by «active transport»?

36 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

37 / 51

Indicate the location of M2 cholinoreceptor type:

38 / 51

The group of nicotinic receptor-blocking drugs consists of:

39 / 51

An antagonist is a substance that:

40 / 51

An agonist is a substance that:

41 / 51

Pharmacodynamics involves the study of following?

42 / 51

Pharmacokinetics is:

 

43 / 51

Acetylcholine is not a specific neurotransmitter at:

44 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

45 / 51

What does “pharmacokinetics” include?

46 / 51

A good local anesthetic agent shouldn’t cause:

47 / 51

Most local anesthetic agents consist of:

48 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

49 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

50 / 51

Pharmacodynamics involves the following?

51 / 51

Pick out the answer which is the most appropriate to the term “receptor”

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