GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test Series 2

1 / 50

1. Carrageen an is a

2 / 50

2. With ferric chloride hydrolysable tannins produce

3 / 50

3. Colophony contains about 90% of

4 / 50

4. Trgacanth contains _______ % of moisture content.

5 / 50

5. Condensed tannins

6 / 50

6. One of the following is also known as Indian gooseberry:

7 / 50

7. Gold beater’s skin test is used to detect the presence of

8 / 50

8. Iaspgol seeds are adulterated with

9 / 50

9. What is the advantage L-Dopa over dopamine?

10 / 50

10. Caramel has ____________ as a chemical constituent.

11 / 50

11. Fiehe’s test is for

12 / 50

12. Myroxylon balsmum is the official source of

13 / 50

13. Potato starch contains ________________ % of ash value.

14 / 50

14. Example of pseudo tannis type is

15 / 50

15. Ashoka bark contains

16 / 50

16. Gumghatti is classified as a

17 / 50

17. The purgative property of myrobalan is due to presence of

18 / 50

18. Synonum of amla is

19 / 50

19. Barium chloride is used for the identification of
(a)  (b)
(c)  (d)

20 / 50

20. Commercially dextran is known as

21 / 50

21. Guggulipid obtained from the commiphoramukul belongs to family

22 / 50

22. Galls are vegetable outgrowths formed on the twigs of

23 / 50

23. Which functional group is transferred by coenzyme pyridoxal phosphate?

24 / 50

24. Indian gum is obtained from

25 / 50

25. Spearmint contains

26 / 50

26. The algae Garcilaria contervoides is used for the preparation of

27 / 50

27. Myrrh is

28 / 50

28. __________% of pectin is obtained from carrots.
(a) 10 (b) 10 to 12
(c) 10 to 15 (d) 5

29 / 50

29. Gallic acid is an active chemical constituent of

30 / 50

30. In which plant trichomes contain resin?

31 / 50

31. On melting double stranded DNA gives more number of?

32 / 50

32. Ferulic acid present in asafoetida on treatment with HCI produces

33 / 50

33. Wheat is derived from

34 / 50

34. Arabin oxidase is present in one of the following carbohydrate:

35 / 50

35. Cymopsis tetragonolobus is a source for

36 / 50

36. Chemically gums consist of

37 / 50

37. The predominant chemical constituent of galls is

38 / 50

38. Triphlachurna contains

39 / 50

39. _______is the Ca++ channel blocker

40 / 50

40. Calcium salt of acidic polysaccharides is present in

41 / 50

41. Gossypol, a compound that has received major attention as male contraceptive
(a) Is a hydroxylated bi naphthalene derivative found in cotton seed oil

(b) Is an aorizanol ester found in rice bran oil

(c) Exhibits toxicity such as hypokalemic-induced paralysis

(d) Acts as an androgen antagonist.

42 / 50

42. Behda consist of dried ripe fruits of Terminalia balerica, which belongs to family

43 / 50

43. Black catechu gives _______ colour with FeCl3

44 / 50

44. Acacia catechu belongs to family

45 / 50

45. All of the following come under Leguminosae except

46 / 50

46. Tannins do not respond to

47 / 50

47. Bahera belongs to __________ family.

48 / 50

48. Hydrolysable tannins on hydrolysis by acid yields

49 / 50

49. Balsams are resinous substances which contain large proportions of

50 / 50

50. Catechins and gallic acids are the examples of

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

2 / 50

Leprosy is also known as.........

3 / 50

Mechanism by which the antiseptic shows their action

4 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

5 / 50

DDS stands for......

6 / 50

Extra intestinal infections include

7 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

8 / 50

Disinfectants are _______

9 / 50

Which of these anti-tubercular drugs are also active against leprosy

10 / 50

Which of the following is commonly used in treatment of acne

11 / 50

IUPAC name of Dapsone is .......................

12 / 50

Functional group present in INH

13 / 50

The heterocyclic nucleus present in sulphadiazine is

14 / 50

Antiseptic have lower bacterial resistance

15 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

16 / 50

Vitamin B6 is administered along with INH to avoid....................

17 / 50

Antiseptic are

18 / 50

Which of the given is not ant amoebic drug

19 / 50

Dienes are the name given to compounds with_______

20 / 50

Storage condition for Rifampicin is...............

21 / 50

Select an anti-leprotic drug among the given...........

22 / 50

Heterocyclic ring present in INH...................

23 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

24 / 50

Name the drug containing pyrazine ring.........

25 / 50

Sulfonamides are mainly used in treatment of eye infection is

26 / 50

Given the following are long acting sulphonamides except.

27 / 50

The C=C bond in the chain of the compound considered is shown by________

28 / 50

Amobiasis is also known as.........................

29 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

30 / 50

Septran is a trade name for

31 / 50

Mechanism of sulfonamides antibacterial effect is

32 / 50

The substituent groups that are commonly associated with benzene are______

33 / 50

Triple bond with two carbon atoms on either side is called_______

34 / 50

Which of the following metal ion shows antimicrobial action.

35 / 50

IUPAC name of INH is ...

36 / 50

Sulfonamides are....................... in action.

37 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

38 / 50

Transmission of amoebiasis occur through_________

39 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

40 / 50

Dapsone is use in combination with...........

41 / 50

Name of drug containing dianilino group........

42 / 50

Functional group present in dapsone is ............

43 / 50

Saturated hydrocarbons are otherwise referred as............................

44 / 50

Protozoan parasite responsible for amebiasis is ________

45 / 50

Which of the following drug belongs to sulfone group

46 / 50

Which of the following drug belongs to 1st line

47 / 50

Major side effects of INH.....

48 / 50

Excystation is _______

49 / 50

Which of the following is an active agent in antiseptic.

50 / 50

Which of the following is not susceptible to alcohol compounds.

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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Spironolactone is a prodrug and its active metabolite is

2 / 50

Undesirable effects of oral contraceptives include all except

3 / 50

Atropine over Dosage may cause all of the following except

4 / 50

Muscarinic receptor M4 are mainly located at

5 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

6 / 50

Morphine affects the eyes by:

7 / 50

Antidote of atropine is

8 / 50

All of the following may enhance the action of sulfonylureas except

9 / 50

In belladonna poisoning convulsions can be controlled by

10 / 50

Major adverse effect of clonidine is

11 / 50

Ganglionic blocking agent may cause all of the following except

12 / 50

Neostigmine may cause all of the following except

13 / 50

In the bioassay the conviction activity in mice is observed during……………use.

14 / 50

Beta agonist used in bronchial asthma exert action by

15 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

16 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

17 / 50

Isolated rabbit jejunum is used

18 / 50

………………drug having highest volume of distribution.

19 / 50

Most common Phase -2nd reaction is

20 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

21 / 50

Bioassays are carried out to:

22 / 50

Mechanism of action of organic phosphate parathion is

23 / 50

Tolbutamide is contraindicated in

24 / 50

Hormones that increase cyclic AMP in the larger organ include all except

25 / 50

Drug of choice in motion sickness is

26 / 50

Most of the drug is absorbed through

27 / 50

Action of D-tubocurarine is

28 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

29 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

30 / 50

Serious unwanted effect of epinephrine is

31 / 50

Drug of choice in the treatment of cardiogenic shock is

32 / 50

Antidote of organo phosphorus poisoning is

33 / 50

Atropine blocks the muscarinic actions of acetylcholine by

34 / 50

Phentolamine is competitive antagonism of

35 / 50

Epinephrine is added to local anaesthetics

36 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

37 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

38 / 50

Alcuronium is a semisynthetic derivative with similar properties of

39 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

40 / 50

Drug having high affinity but low intrinsic activity is called

41 / 50

Which of the following a is directly acting sympathomimetic agent?

42 / 50

Sweating is inhibited by

43 / 50

Which of the following is CYP450 enzyme inhibitor?

44 / 50

Which of the following receptor shows the slowest response?

45 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

46 / 50

All of the following statement related to neostigmine are correct except

47 / 50

Local anesthetics produce:

48 / 50

Darifenacin is a

49 / 50

In urinary incontinence following drug is widely used:

50 / 50

Pilocarpine is classified as

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GPAT Mock Test-2024

1 / 100

Aliskiren acts by

2 / 100

For glyburide, all of the following metabolic reactions are logical except:

3 / 100

Eugenol is present in

4 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

5 / 100

Class 100 area is referred to

6 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

7 / 100

In which of the following techniques, the sample is kept below triple point?

8 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

9 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

10 / 100

The amount of barbaloin present in Aloe vera is

11 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

12 / 100

The given antibiotic is an example of ansamycins:

13 / 100

Triterpenoids are active constituents of

14 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

15 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

16 / 100

Which of the following non-opioid analgesics is a prodrug?

17 / 100

Artemisinin contains the following group in its structure:

18 / 100

Choose the right combination:

19 / 100

Sildenafil is used for treatment of one of the following
disorders:

20 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

21 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

22 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

23 / 100

The temperature condition for storage of drug products under cold temperature is given as

24 / 100

The role of borax in cold creams is

25 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

26 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

27 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

28 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

29 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

30 / 100

Alkaloids are not precipitated by

31 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

32 / 100

Which one of the following is a plasminogen activator?

33 / 100

Drugs in suspensions and semi-solid formulations always degrade by

34 / 100

Which one of the following drugs is not a typical antipsychotic agent?

35 / 100

Drugs following one compartment open model pharmacokinetics eliminate

36 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

37 / 100

The chemical behaviour of morphine alkaloid is

38 / 100

Humectants added in cosmetic preparations generally act by

39 / 100

The characteristic of non-linear pharmacokinetics includes:

40 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

41 / 100

Oxidative phosphorylation involves

42 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

43 / 100

In nail polish, the following polymer is used as a film-former:

44 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

45 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

46 / 100

The following protein/polypeptide has a quaternary structure:

47 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

48 / 100

Guggul lipids are obtained from

49 / 100

X-ray crystallographic analysis of an optically active compound determines its

50 / 100

Quassia wood is adulterated with

51 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

52 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

53 / 100

The applicability of Noyes-Whitney equation is to describe

54 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

55 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

56 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

57 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

58 / 100

Identify the one rational combination which has clinical benefit:

59 / 100

The healing agent used in hand creams is

60 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

61 / 100

Nicotinic action of acetylcholine is blocked by the drug

62 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

63 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

64 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

65 / 100

Measurement of inulin renal clearance is a measure for

66 / 100

Ganciclovir is mainly used for the treatment of infection caused by

67 / 100

Digitalis toxicity is enhanced by co-administration of

68 / 100

Aminotransferases usually requires the following for their activity:

69 / 100

An example of N-glycoside is

70 / 100

Amitryptyline is synthesized from the following starting material:

71 / 100

Cyclophosphamide as anticancer agent acts as

72 / 100

Gingkgo biloba is used for its

73 / 100

Which one of the following statements is wrong?

74 / 100

One of the following statements is not true:

75 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

76 / 100

An isosteric replacement for carboxylic acid group is

77 / 100

Coulter counter is used in determination of

78 / 100

Geriatric population should be included in the following phase of clinical trials:

79 / 100

Ethambutol molecule has

80 / 100

Rabies vaccine (living) is prepared using

81 / 100

At physiological pH, the following compound would be mostly in the

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82 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

83 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

84 / 100

Bacopa monnieri plant belongs to the family

85 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

86 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

87 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

88 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

89 / 100

The ability of human eye using illuminated area to detect a particle is limited to

90 / 100

In thiazides, following substituent is essential for diuretic activity:

91 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

92 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

93 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

94 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

95 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

96 / 100

Selective serotonin reuptake inhibitor is

97 / 100

Which one of the following statements is wrong?

98 / 100

Tropane alkaloids are not present in

99 / 100

Anisocytic stomata are present in

100 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

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Pharmacology MCQs for DPEE and GPAT

1 / 51

Acetylcholine is not a specific neurotransmitter at:

2 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

3 / 51

Indicate a muscarinic receptor-blocking drug:

4 / 51

Pharmacodynamics involves the following?

5 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

6 / 51

What does “pharmacokinetics” include?

7 / 51

What does “pharmacokinetics” include?

8 / 51

M3 receptor subtype is located:

9 / 51

Characteristics of carbachol include all of the following EXCEPT:

10 / 51

The group of nicotinic receptor-blocking drugs consists of:

11 / 51

An agonist is a substance that:

12 / 51

Muscarinic receptors are located in:

13 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

14 / 51

Indicate the location of M2 cholinoreceptor type:

15 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

16 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

17 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

18 / 51

What does “pharmacokinetics” include?

19 / 51

Pick out the answer which is the most appropriate to the term “receptor”

20 / 51

Pharmacodynamics involves the study of following?

21 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

22 / 51

Target proteins which a drug molecule binds are:

23 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

24 / 51

The reasons determing bioavailability are:

25 / 51

Most local anesthetic agents consist of:

26 / 51

Ionizable group is responsible for:

27 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

28 / 51

Which of the following agents is a ganglion-blocking drug?

29 / 51

A hydrophilic medicinal agent has the following property:

30 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

31 / 51

The mechanism of atropine action is:

32 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

33 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

34 / 51

An antagonist is a substance that:

35 / 51

Acetylcholine is not used in clinical practice because:

36 / 51

Local anesthetics produce:

37 / 51

Parasympathomimetic drugs cause:

38 / 51

Pharmacodynamics involves the study of following EXCEPT:

39 / 51

What kind of substances can’t permeate membranes by passive diffusion?

40 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

41 / 51

Pharmacokinetics is:

 

42 / 51

What does the term “bioavailability” mean?

43 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

44 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

45 / 51

A good local anesthetic agent shouldn’t cause:

46 / 51

What is implied by «active transport»?

47 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

48 / 51

The main mechanism of most drugs absorption in GI tract is:

49 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

50 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

51 / 51

What does “affinity” mean?

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