GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
2029
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GPAT Mock Test-2024

1 / 100

An isosteric replacement for carboxylic acid group is

2 / 100

The role of borax in cold creams is

3 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

4 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

5 / 100

Choose the right combination:

6 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

7 / 100

Cyclophosphamide as anticancer agent acts as

8 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

9 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

10 / 100

The applicability of Noyes-Whitney equation is to describe

11 / 100

Digitalis toxicity is enhanced by co-administration of

12 / 100

Artemisinin contains the following group in its structure:

13 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

14 / 100

Quassia wood is adulterated with

15 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

16 / 100

The temperature condition for storage of drug products under cold temperature is given as

17 / 100

Gingkgo biloba is used for its

18 / 100

Amitryptyline is synthesized from the following starting material:

19 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

20 / 100

The given antibiotic is an example of ansamycins:

21 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

22 / 100

Ganciclovir is mainly used for the treatment of infection caused by

23 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

24 / 100

Aminotransferases usually requires the following for their activity:

25 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

26 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

27 / 100

The following protein/polypeptide has a quaternary structure:

28 / 100

Which one of the following statements is wrong?

29 / 100

Class 100 area is referred to

30 / 100

In thiazides, following substituent is essential for diuretic activity:

31 / 100

Which one of the following drugs is not a typical antipsychotic agent?

32 / 100

Nicotinic action of acetylcholine is blocked by the drug

33 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

34 / 100

Bacopa monnieri plant belongs to the family

35 / 100

In which of the following techniques, the sample is kept below triple point?

36 / 100

Measurement of inulin renal clearance is a measure for

37 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

38 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

39 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

40 / 100

Anisocytic stomata are present in

41 / 100

Identify the one rational combination which has clinical benefit:

42 / 100

Which of the following non-opioid analgesics is a prodrug?

43 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

44 / 100

Which one of the following statements is wrong?

45 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

46 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

47 / 100

In nail polish, the following polymer is used as a film-former:

48 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

49 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

50 / 100

One of the following statements is not true:

51 / 100

The chemical behaviour of morphine alkaloid is

52 / 100

Coulter counter is used in determination of

53 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

54 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

55 / 100

At physiological pH, the following compound would be mostly in the

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56 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

57 / 100

The healing agent used in hand creams is

58 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

59 / 100

Alkaloids are not precipitated by

60 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

61 / 100

Selective serotonin reuptake inhibitor is

62 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

63 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

64 / 100

Tropane alkaloids are not present in

65 / 100

Triterpenoids are active constituents of

66 / 100

X-ray crystallographic analysis of an optically active compound determines its

67 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

68 / 100

The characteristic of non-linear pharmacokinetics includes:

69 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

70 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

71 / 100

Rabies vaccine (living) is prepared using

72 / 100

Which one of the following is a plasminogen activator?

73 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

74 / 100

For glyburide, all of the following metabolic reactions are logical except:

75 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

76 / 100

Geriatric population should be included in the following phase of clinical trials:

77 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

78 / 100

Humectants added in cosmetic preparations generally act by

79 / 100

An example of N-glycoside is

80 / 100

Oxidative phosphorylation involves

81 / 100

Drugs in suspensions and semi-solid formulations always degrade by

82 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

83 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

84 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

85 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

86 / 100

Drugs following one compartment open model pharmacokinetics eliminate

87 / 100

Guggul lipids are obtained from

88 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

89 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

90 / 100

Aliskiren acts by

91 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

92 / 100

The amount of barbaloin present in Aloe vera is

93 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

94 / 100

The ability of human eye using illuminated area to detect a particle is limited to

95 / 100

Eugenol is present in

96 / 100

Sildenafil is used for treatment of one of the following
disorders:

97 / 100

Ethambutol molecule has

98 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

99 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

100 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

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The average score is 20%

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Excystation is _______

2 / 50

Amobiasis is also known as.........................

3 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

4 / 50

Triple bond with two carbon atoms on either side is called_______

5 / 50

Functional group present in dapsone is ............

6 / 50

IUPAC name of Dapsone is .......................

7 / 50

Which of the given is not ant amoebic drug

8 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

9 / 50

Storage condition for Rifampicin is...............

10 / 50

Vitamin B6 is administered along with INH to avoid....................

11 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

12 / 50

Dienes are the name given to compounds with_______

13 / 50

Which of the following metal ion shows antimicrobial action.

14 / 50

Antiseptic have lower bacterial resistance

15 / 50

Transmission of amoebiasis occur through_________

16 / 50

Select an anti-leprotic drug among the given...........

17 / 50

Extra intestinal infections include

18 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

19 / 50

Functional group present in INH

20 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

21 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

22 / 50

The substituent groups that are commonly associated with benzene are______

23 / 50

Which of the following is commonly used in treatment of acne

24 / 50

Major side effects of INH.....

25 / 50

Given the following are long acting sulphonamides except.

26 / 50

DDS stands for......

27 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

28 / 50

Mechanism of sulfonamides antibacterial effect is

29 / 50

The heterocyclic nucleus present in sulphadiazine is

30 / 50

Antiseptic are

31 / 50

IUPAC name of INH is ...

32 / 50

Heterocyclic ring present in INH...................

33 / 50

Protozoan parasite responsible for amebiasis is ________

34 / 50

Dapsone is use in combination with...........

35 / 50

Sulfonamides are mainly used in treatment of eye infection is

36 / 50

Name the drug containing pyrazine ring.........

37 / 50

Which of the following is an active agent in antiseptic.

38 / 50

Septran is a trade name for

39 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

40 / 50

Name of drug containing dianilino group........

41 / 50

Which of the following drug belongs to 1st line

42 / 50

Which of the following is not susceptible to alcohol compounds.

43 / 50

Saturated hydrocarbons are otherwise referred as............................

44 / 50

Mechanism by which the antiseptic shows their action

45 / 50

Which of these anti-tubercular drugs are also active against leprosy

46 / 50

Sulfonamides are....................... in action.

47 / 50

The C=C bond in the chain of the compound considered is shown by________

48 / 50

Leprosy is also known as.........

49 / 50

Which of the following drug belongs to sulfone group

50 / 50

Disinfectants are _______

Your score is

The average score is 22%

0%

2556
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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Phentolamine is competitive antagonism of

2 / 50

Major adverse effect of clonidine is

3 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

4 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

5 / 50

Morphine affects the eyes by:

6 / 50

Atropine blocks the muscarinic actions of acetylcholine by

7 / 50

Undesirable effects of oral contraceptives include all except

8 / 50

Serious unwanted effect of epinephrine is

9 / 50

Isolated rabbit jejunum is used

10 / 50

In belladonna poisoning convulsions can be controlled by

11 / 50

Pilocarpine is classified as

12 / 50

Epinephrine is added to local anaesthetics

13 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

14 / 50

Action of D-tubocurarine is

15 / 50

In urinary incontinence following drug is widely used:

16 / 50

Darifenacin is a

17 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

18 / 50

Alcuronium is a semisynthetic derivative with similar properties of

19 / 50

All of the following statement related to neostigmine are correct except

20 / 50

Most common Phase -2nd reaction is

21 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

22 / 50

Ganglionic blocking agent may cause all of the following except

23 / 50

Drug of choice in the treatment of cardiogenic shock is

24 / 50

Antidote of organo phosphorus poisoning is

25 / 50

Bioassays are carried out to:

26 / 50

Antidote of atropine is

27 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

28 / 50

Neostigmine may cause all of the following except

29 / 50

Drug having high affinity but low intrinsic activity is called

30 / 50

In the bioassay the conviction activity in mice is observed during……………use.

31 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

32 / 50

Drug of choice in motion sickness is

33 / 50

Muscarinic receptor M4 are mainly located at

34 / 50

Which of the following receptor shows the slowest response?

35 / 50

………………drug having highest volume of distribution.

36 / 50

Most of the drug is absorbed through

37 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

38 / 50

Spironolactone is a prodrug and its active metabolite is

39 / 50

Tolbutamide is contraindicated in

40 / 50

Mechanism of action of organic phosphate parathion is

41 / 50

Local anesthetics produce:

42 / 50

Beta agonist used in bronchial asthma exert action by

43 / 50

All of the following may enhance the action of sulfonylureas except

44 / 50

Sweating is inhibited by

45 / 50

Which of the following a is directly acting sympathomimetic agent?

46 / 50

Atropine over Dosage may cause all of the following except

47 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

48 / 50

Hormones that increase cyclic AMP in the larger organ include all except

49 / 50

Which of the following is CYP450 enzyme inhibitor?

50 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

Your score is

The average score is 30%

0%

1699

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

1. Pharmacy council of India has ______ state government nominated member(s)

2 / 25

2. Form 20 states that

3 / 25

3. "Schedule F3" is related with

4 / 25

4. Appendix II is about

5 / 25

5. Manufacturing and analytical records of cosmetics are included in which schedule?

6 / 25

6. In AICTE the chairman is appointed by

7 / 25

7. Pharmacy Act is established in

8 / 25

8. Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

9 / 25

9. Which pharmaceutical product is not included in Schedule C?

10 / 25

10. Spurious drug comes under

11 / 25

11. Nominated or elected members in "State Pharmacy Council" hold office for a term of

12 / 25

12. Schedule M, states that

13 / 25

13. Private testing laboratory for carrying out tests on drugs requires.

14 / 25

14. Standard for disinfectant fluids come under.

15 / 25

15. Insulin comes under

16 / 25

16. Pharmacy Council of India is doing all of below func tions except

17 / 25

17. "Ampicillin capsule should be used within 24 months." This statement comes under

18 / 25

18. Insulin injection according to Schedule P is should be stored

19 / 25

19. In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

20 / 25

20. Crocin is sale under

21 / 25

21. Blood Bank comes under the schedule

22 / 25

22. If the drug contains in filthy, putrid or decomposed substance then is known as

23 / 25

23. Names of drugs which shall be marketed under generic names only come under

24 / 25

24. How many members are elected among themselves by registered Pharmacist of state

25 / 25

25. One of the following forms is needed for the cosmetic manufacture.

Your score is

The average score is 39%

0%

569
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Pharmacology MCQs for DPEE and GPAT

1 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

2 / 51

Pharmacodynamics involves the following?

3 / 51

What does the term “bioavailability” mean?

4 / 51

Indicate a muscarinic receptor-blocking drug:

5 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

6 / 51

A hydrophilic medicinal agent has the following property:

7 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

8 / 51

Target proteins which a drug molecule binds are:

9 / 51

Pick out the answer which is the most appropriate to the term “receptor”

10 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

11 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

12 / 51

Ionizable group is responsible for:

13 / 51

Characteristics of carbachol include all of the following EXCEPT:

14 / 51

Which of the following agents is a ganglion-blocking drug?

15 / 51

What is implied by «active transport»?

16 / 51

What kind of substances can’t permeate membranes by passive diffusion?

17 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

18 / 51

Acetylcholine is not a specific neurotransmitter at:

19 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

20 / 51

Most local anesthetic agents consist of:

21 / 51

Acetylcholine is not used in clinical practice because:

22 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

23 / 51

The main mechanism of most drugs absorption in GI tract is:

24 / 51

Indicate the location of M2 cholinoreceptor type:

25 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

26 / 51

An agonist is a substance that:

27 / 51

Parasympathomimetic drugs cause:

28 / 51

The reasons determing bioavailability are:

29 / 51

Pharmacokinetics is:

 

30 / 51

Pharmacodynamics involves the study of following?

31 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

32 / 51

Local anesthetics produce:

33 / 51

What does “pharmacokinetics” include?

34 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

35 / 51

The group of nicotinic receptor-blocking drugs consists of:

36 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

37 / 51

M3 receptor subtype is located:

38 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

39 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

40 / 51

An antagonist is a substance that:

41 / 51

A good local anesthetic agent shouldn’t cause:

42 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

43 / 51

The mechanism of atropine action is:

44 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

45 / 51

Muscarinic receptors are located in:

46 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

47 / 51

What does “affinity” mean?

48 / 51

What does “pharmacokinetics” include?

49 / 51

What does “pharmacokinetics” include?

50 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

51 / 51

Pharmacodynamics involves the study of following EXCEPT:

Your score is

The average score is 24%

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