An isosteric replacement for carboxylic acid group is

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

Which one of the following is not an ex-officio member of Pharmacy Council of India?

At physiological pH, the following compound would be mostly in the

The healing agent used in hand creams is

The given antibiotic is an example of ansamycins:

Aminotransferases usually requires the following for their activity:

The role of borax in cold creams is

Humectants added in cosmetic preparations generally act by

The rate limiting step in cholesterol biosynthesis is one of the following:

Which one of the following drugs is not a typical antipsychotic agent?

Selective serotonin reuptake inhibitor is

Class 100 area is referred to

The following protein/polypeptide has a quaternary structure:

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

X-ray crystallographic analysis of an optically active compound determines its

Measurement of inulin renal clearance is a measure for

An example of N-glycoside is

Which one of the following drugs does not act through G-Protein coupled receptors?

Nicotinic action of acetylcholine is blocked by the drug

For glyburide, all of the following metabolic reactions are logical except:

One of the following statements is not true:

Guggul lipids are obtained from

Tropane alkaloids are not present in

Identify the one rational combination which has clinical benefit:

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

Ethambutol molecule has

The temperature condition for storage of drug products under cold temperature is given as

The chemical behaviour of morphine alkaloid is

Anisocytic stomata are present in

Ganciclovir is mainly used for the treatment of infection caused by

Many xenobiotics are oxidized by cytochrome P450 in order to

The applicability of Noyes-Whitney equation is to describe

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

Which one of the following statements is wrong?

Streptomycin cannot be given orally for treatment of tuberculosis because

Coulter counter is used in determination of

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

Which one of the following statements is wrong?

Eugenol is present in

In nail polish, the following polymer is used as a film-former:

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

Drugs following one compartment open model pharmacokinetics eliminate

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

The amount of barbaloin present in Aloe vera is

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

Myasthenia gravis is diagnosed with improved neuromuscular function by using

Drugs in suspensions and semi-solid formulations always degrade by

In the mixing of thymol and menthol, the following type of incompatibility occurs:

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

Rabies vaccine (living) is prepared using

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

Aliskiren acts by

Triterpenoids are active constituents of

One mg of Lycopodium spores used in quantitative microscopy contains an average of

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

Purity of water can be assessed by determining one of its following properties instrumentally:

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

Gingkgo biloba is used for its

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

Quassia wood is adulterated with

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

Choose the right combination:

Digitalis toxicity is enhanced by co-administration of

Which one of the following is a plasminogen activator?

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

Alkaloids are not precipitated by

Amitryptyline is synthesized from the following starting material:

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

Bacopa monnieri plant belongs to the family

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

Oxidative phosphorylation involves

The ability of human eye using illuminated area to detect a particle is limited to

Which one of the following is a flocculating agent for a negatively charged drug?

Geriatric population should be included in the following phase of clinical trials:

In thiazides, following substituent is essential for diuretic activity:

In which of the following techniques, the sample is kept below triple point?

The characteristic of non-linear pharmacokinetics includes:

Which of the following non-opioid analgesics is a prodrug?

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

Indicate the HPLC detector that is most sensitive to change in temperature:

Artemisinin contains the following group in its structure:

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

Cyclophosphamide as anticancer agent acts as

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

Sildenafil is used for treatment of one of the following
disorders: