GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
1400
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GPAT Mock Test-2024

1 / 100

One of the following statements is not true:

2 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

3 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

4 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

5 / 100

Measurement of inulin renal clearance is a measure for

6 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

7 / 100

In thiazides, following substituent is essential for diuretic activity:

8 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

9 / 100

Ethambutol molecule has

10 / 100

Cyclophosphamide as anticancer agent acts as

11 / 100

The healing agent used in hand creams is

12 / 100

For glyburide, all of the following metabolic reactions are logical except:

13 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

14 / 100

Which of the following non-opioid analgesics is a prodrug?

15 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

16 / 100

Which one of the following is a plasminogen activator?

17 / 100

Aliskiren acts by

18 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

19 / 100

Which one of the following statements is wrong?

20 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

21 / 100

The given antibiotic is an example of ansamycins:

22 / 100

The applicability of Noyes-Whitney equation is to describe

23 / 100

Alkaloids are not precipitated by

24 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

25 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

26 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

27 / 100

The chemical behaviour of morphine alkaloid is

28 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

29 / 100

Drugs in suspensions and semi-solid formulations always degrade by

30 / 100

The characteristic of non-linear pharmacokinetics includes:

31 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

32 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

33 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

34 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

35 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

36 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

37 / 100

Which one of the following statements is wrong?

38 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

39 / 100

Class 100 area is referred to

40 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

41 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

42 / 100

Aminotransferases usually requires the following for their activity:

43 / 100

Triterpenoids are active constituents of

44 / 100

Which one of the following drugs is not a typical antipsychotic agent?

45 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

46 / 100

Selective serotonin reuptake inhibitor is

47 / 100

Coulter counter is used in determination of

48 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

49 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

50 / 100

The ability of human eye using illuminated area to detect a particle is limited to

51 / 100

An example of N-glycoside is

52 / 100

Humectants added in cosmetic preparations generally act by

53 / 100

Gingkgo biloba is used for its

54 / 100

Anisocytic stomata are present in

55 / 100

The amount of barbaloin present in Aloe vera is

56 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

57 / 100

Oxidative phosphorylation involves

58 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

59 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

60 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

61 / 100

The temperature condition for storage of drug products under cold temperature is given as

62 / 100

Artemisinin contains the following group in its structure:

63 / 100

Tropane alkaloids are not present in

64 / 100

In nail polish, the following polymer is used as a film-former:

65 / 100

The following protein/polypeptide has a quaternary structure:

66 / 100

Guggul lipids are obtained from

67 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

68 / 100

Eugenol is present in

69 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

70 / 100

Nicotinic action of acetylcholine is blocked by the drug

71 / 100

In which of the following techniques, the sample is kept below triple point?

72 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

73 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

74 / 100

The role of borax in cold creams is

75 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

76 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

77 / 100

Bacopa monnieri plant belongs to the family

78 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

79 / 100

Sildenafil is used for treatment of one of the following
disorders:

80 / 100

Amitryptyline is synthesized from the following starting material:

81 / 100

An isosteric replacement for carboxylic acid group is

82 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

83 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

84 / 100

Geriatric population should be included in the following phase of clinical trials:

85 / 100

Choose the right combination:

86 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

87 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

88 / 100

Quassia wood is adulterated with

89 / 100

Drugs following one compartment open model pharmacokinetics eliminate

90 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

91 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

92 / 100

Identify the one rational combination which has clinical benefit:

93 / 100

Ganciclovir is mainly used for the treatment of infection caused by

94 / 100

X-ray crystallographic analysis of an optically active compound determines its

95 / 100

At physiological pH, the following compound would be mostly in the

Capture | Noteskarts, D.Pharma Notes PDF, D.Pharma 1st year Notes, Pharmacy Notes Noteskarts GPAT Mock Test 2023

96 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

97 / 100

Rabies vaccine (living) is prepared using

98 / 100

Digitalis toxicity is enhanced by co-administration of

99 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

100 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Name of drug containing dianilino group........

2 / 50

Major side effects of INH.....

3 / 50

Which of the given is not ant amoebic drug

4 / 50

Vitamin B6 is administered along with INH to avoid....................

5 / 50

Sulfonamides are....................... in action.

6 / 50

Leprosy is also known as.........

7 / 50

Sulfonamides are mainly used in treatment of eye infection is

8 / 50

Antiseptic have lower bacterial resistance

9 / 50

Name the drug containing pyrazine ring.........

10 / 50

Heterocyclic ring present in INH...................

11 / 50

Saturated hydrocarbons are otherwise referred as............................

12 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

13 / 50

The C=C bond in the chain of the compound considered is shown by________

14 / 50

Functional group present in dapsone is ............

15 / 50

Mechanism by which the antiseptic shows their action

16 / 50

Given the following are long acting sulphonamides except.

17 / 50

IUPAC name of INH is ...

18 / 50

Storage condition for Rifampicin is...............

19 / 50

Extra intestinal infections include

20 / 50

Which of the following is not susceptible to alcohol compounds.

21 / 50

Mechanism of sulfonamides antibacterial effect is

22 / 50

Triple bond with two carbon atoms on either side is called_______

23 / 50

Functional group present in INH

24 / 50

IUPAC name of Dapsone is .......................

25 / 50

Which of the following is an active agent in antiseptic.

26 / 50

DDS stands for......

27 / 50

Dienes are the name given to compounds with_______

28 / 50

Which of the following metal ion shows antimicrobial action.

29 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

30 / 50

Which of the following drug belongs to 1st line

31 / 50

Select an anti-leprotic drug among the given...........

32 / 50

The substituent groups that are commonly associated with benzene are______

33 / 50

Transmission of amoebiasis occur through_________

34 / 50

Which of these anti-tubercular drugs are also active against leprosy

35 / 50

The heterocyclic nucleus present in sulphadiazine is

36 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

37 / 50

Dapsone is use in combination with...........

38 / 50

Amobiasis is also known as.........................

39 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

40 / 50

Antiseptic are

41 / 50

Excystation is _______

42 / 50

Disinfectants are _______

43 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

44 / 50

Protozoan parasite responsible for amebiasis is ________

45 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

46 / 50

Which of the following drug belongs to sulfone group

47 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

48 / 50

Septran is a trade name for

49 / 50

Which of the following is commonly used in treatment of acne

50 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

Your score is

The average score is 22%

0%

2151
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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

2 / 50

Sweating is inhibited by

3 / 50

All of the following may enhance the action of sulfonylureas except

4 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

5 / 50

Hormones that increase cyclic AMP in the larger organ include all except

6 / 50

Pilocarpine is classified as

7 / 50

Antidote of atropine is

8 / 50

Drug having high affinity but low intrinsic activity is called

9 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

10 / 50

Epinephrine is added to local anaesthetics

11 / 50

Spironolactone is a prodrug and its active metabolite is

12 / 50

Mechanism of action of organic phosphate parathion is

13 / 50

Tolbutamide is contraindicated in

14 / 50

Which of the following is CYP450 enzyme inhibitor?

15 / 50

All of the following statement related to neostigmine are correct except

16 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

17 / 50

Bioassays are carried out to:

18 / 50

Morphine affects the eyes by:

19 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

20 / 50

Most common Phase -2nd reaction is

21 / 50

Which of the following receptor shows the slowest response?

22 / 50

Major adverse effect of clonidine is

23 / 50

Action of D-tubocurarine is

24 / 50

Atropine blocks the muscarinic actions of acetylcholine by

25 / 50

Ganglionic blocking agent may cause all of the following except

26 / 50

Beta agonist used in bronchial asthma exert action by

27 / 50

Drug of choice in motion sickness is

28 / 50

In urinary incontinence following drug is widely used:

29 / 50

In the bioassay the conviction activity in mice is observed during……………use.

30 / 50

Local anesthetics produce:

31 / 50

Darifenacin is a

32 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

33 / 50

Antidote of organo phosphorus poisoning is

34 / 50

Which of the following a is directly acting sympathomimetic agent?

35 / 50

Alcuronium is a semisynthetic derivative with similar properties of

36 / 50

Serious unwanted effect of epinephrine is

37 / 50

Drug of choice in the treatment of cardiogenic shock is

38 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

39 / 50

Muscarinic receptor M4 are mainly located at

40 / 50

Atropine over Dosage may cause all of the following except

41 / 50

Neostigmine may cause all of the following except

42 / 50

Isolated rabbit jejunum is used

43 / 50

Undesirable effects of oral contraceptives include all except

44 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

45 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

46 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

47 / 50

Most of the drug is absorbed through

48 / 50

In belladonna poisoning convulsions can be controlled by

49 / 50

Phentolamine is competitive antagonism of

50 / 50

………………drug having highest volume of distribution.

Your score is

The average score is 30%

0%

1433

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

1. "Schedule F3" is related with

2 / 25

2. One of the following forms is needed for the cosmetic manufacture.

3 / 25

3. If the drug contains in filthy, putrid or decomposed substance then is known as

4 / 25

4. Private testing laboratory for carrying out tests on drugs requires.

5 / 25

5. Pharmacy council of India has ______ state government nominated member(s)

6 / 25

6. How many members are elected among themselves by registered Pharmacist of state

7 / 25

7. In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

8 / 25

8. Pharmacy Act is established in

9 / 25

9. Insulin injection according to Schedule P is should be stored

10 / 25

10. In AICTE the chairman is appointed by

11 / 25

11. Which pharmaceutical product is not included in Schedule C?

12 / 25

12. Nominated or elected members in "State Pharmacy Council" hold office for a term of

13 / 25

13. Names of drugs which shall be marketed under generic names only come under

14 / 25

14. Standard for disinfectant fluids come under.

15 / 25

15. Schedule M, states that

16 / 25

16. Pharmacy Council of India is doing all of below func tions except

17 / 25

17. Form 20 states that

18 / 25

18. Appendix II is about

19 / 25

19. Blood Bank comes under the schedule

20 / 25

20. Spurious drug comes under

21 / 25

21. Insulin comes under

22 / 25

22. Manufacturing and analytical records of cosmetics are included in which schedule?

23 / 25

23. Crocin is sale under

24 / 25

24. Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

25 / 25

25. "Ampicillin capsule should be used within 24 months." This statement comes under

Your score is

The average score is 38%

0%

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Pharmacology MCQs for DPEE and GPAT

1 / 51

The main mechanism of most drugs absorption in GI tract is:

2 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

3 / 51

Most local anesthetic agents consist of:

4 / 51

What does the term “bioavailability” mean?

5 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

6 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

7 / 51

An agonist is a substance that:

8 / 51

A good local anesthetic agent shouldn’t cause:

9 / 51

Pharmacodynamics involves the study of following?

10 / 51

Characteristics of carbachol include all of the following EXCEPT:

11 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

12 / 51

What does “pharmacokinetics” include?

13 / 51

The mechanism of atropine action is:

14 / 51

Ionizable group is responsible for:

15 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

16 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

17 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

18 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

19 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

20 / 51

Pharmacodynamics involves the following?

21 / 51

Parasympathomimetic drugs cause:

22 / 51

What does “affinity” mean?

23 / 51

What does “pharmacokinetics” include?

24 / 51

What is implied by «active transport»?

25 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

26 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

27 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

28 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

29 / 51

Acetylcholine is not a specific neurotransmitter at:

30 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

31 / 51

Pharmacodynamics involves the study of following EXCEPT:

32 / 51

Pharmacokinetics is:

 

33 / 51

Acetylcholine is not used in clinical practice because:

34 / 51

The reasons determing bioavailability are:

35 / 51

Pick out the answer which is the most appropriate to the term “receptor”

36 / 51

Indicate a muscarinic receptor-blocking drug:

37 / 51

Indicate the location of M2 cholinoreceptor type:

38 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

39 / 51

Target proteins which a drug molecule binds are:

40 / 51

What does “pharmacokinetics” include?

41 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

42 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

43 / 51

M3 receptor subtype is located:

44 / 51

An antagonist is a substance that:

45 / 51

The group of nicotinic receptor-blocking drugs consists of:

46 / 51

A hydrophilic medicinal agent has the following property:

47 / 51

Local anesthetics produce:

48 / 51

Which of the following agents is a ganglion-blocking drug?

49 / 51

What kind of substances can’t permeate membranes by passive diffusion?

50 / 51

Muscarinic receptors are located in:

51 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

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