GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
2208
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GPAT Mock Test-2024

1 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

2 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

3 / 100

At physiological pH, the following compound would be mostly in the

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4 / 100

Alkaloids are not precipitated by

5 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

6 / 100

Digitalis toxicity is enhanced by co-administration of

7 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

8 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

9 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

10 / 100

Sildenafil is used for treatment of one of the following
disorders:

11 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

12 / 100

Quassia wood is adulterated with

13 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

14 / 100

Drugs in suspensions and semi-solid formulations always degrade by

15 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

16 / 100

Amitryptyline is synthesized from the following starting material:

17 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

18 / 100

Bacopa monnieri plant belongs to the family

19 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

20 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

21 / 100

Tropane alkaloids are not present in

22 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

23 / 100

Which one of the following is a plasminogen activator?

24 / 100

Which of the following non-opioid analgesics is a prodrug?

25 / 100

The following protein/polypeptide has a quaternary structure:

26 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

27 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

28 / 100

Humectants added in cosmetic preparations generally act by

29 / 100

An isosteric replacement for carboxylic acid group is

30 / 100

Class 100 area is referred to

31 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

32 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

33 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

34 / 100

Choose the right combination:

35 / 100

For glyburide, all of the following metabolic reactions are logical except:

36 / 100

Aminotransferases usually requires the following for their activity:

37 / 100

Ethambutol molecule has

38 / 100

The given antibiotic is an example of ansamycins:

39 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

40 / 100

The temperature condition for storage of drug products under cold temperature is given as

41 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

42 / 100

The characteristic of non-linear pharmacokinetics includes:

43 / 100

The applicability of Noyes-Whitney equation is to describe

44 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

45 / 100

Identify the one rational combination which has clinical benefit:

46 / 100

Which one of the following drugs is not a typical antipsychotic agent?

47 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

48 / 100

Cyclophosphamide as anticancer agent acts as

49 / 100

Gingkgo biloba is used for its

50 / 100

One of the following statements is not true:

51 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

52 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

53 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

54 / 100

In which of the following techniques, the sample is kept below triple point?

55 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

56 / 100

Artemisinin contains the following group in its structure:

57 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

58 / 100

Ganciclovir is mainly used for the treatment of infection caused by

59 / 100

Oxidative phosphorylation involves

60 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

61 / 100

The healing agent used in hand creams is

62 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

63 / 100

Rabies vaccine (living) is prepared using

64 / 100

Which one of the following statements is wrong?

65 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

66 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

67 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

68 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

69 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

70 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

71 / 100

Aliskiren acts by

72 / 100

Coulter counter is used in determination of

73 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

74 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

75 / 100

An example of N-glycoside is

76 / 100

The role of borax in cold creams is

77 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

78 / 100

Measurement of inulin renal clearance is a measure for

79 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

80 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

81 / 100

In nail polish, the following polymer is used as a film-former:

82 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

83 / 100

Selective serotonin reuptake inhibitor is

84 / 100

Nicotinic action of acetylcholine is blocked by the drug

85 / 100

Guggul lipids are obtained from

86 / 100

The chemical behaviour of morphine alkaloid is

87 / 100

Drugs following one compartment open model pharmacokinetics eliminate

88 / 100

Eugenol is present in

89 / 100

Geriatric population should be included in the following phase of clinical trials:

90 / 100

Triterpenoids are active constituents of

91 / 100

The amount of barbaloin present in Aloe vera is

92 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

93 / 100

Which one of the following statements is wrong?

94 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

95 / 100

The ability of human eye using illuminated area to detect a particle is limited to

96 / 100

Anisocytic stomata are present in

97 / 100

X-ray crystallographic analysis of an optically active compound determines its

98 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

99 / 100

In thiazides, following substituent is essential for diuretic activity:

100 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

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The average score is 20%

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

2 / 50

Which of the following drug belongs to sulfone group

3 / 50

Antiseptic are

4 / 50

Functional group present in dapsone is ............

5 / 50

The C=C bond in the chain of the compound considered is shown by________

6 / 50

Heterocyclic ring present in INH...................

7 / 50

Septran is a trade name for

8 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

9 / 50

The heterocyclic nucleus present in sulphadiazine is

10 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

11 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

12 / 50

IUPAC name of Dapsone is .......................

13 / 50

Which of these anti-tubercular drugs are also active against leprosy

14 / 50

Mechanism by which the antiseptic shows their action

15 / 50

Disinfectants are _______

16 / 50

Name of drug containing dianilino group........

17 / 50

Major side effects of INH.....

18 / 50

Sulfonamides are....................... in action.

19 / 50

Protozoan parasite responsible for amebiasis is ________

20 / 50

The substituent groups that are commonly associated with benzene are______

21 / 50

Select an anti-leprotic drug among the given...........

22 / 50

Which of the following metal ion shows antimicrobial action.

23 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

24 / 50

IUPAC name of INH is ...

25 / 50

Dienes are the name given to compounds with_______

26 / 50

Which of the following is not susceptible to alcohol compounds.

27 / 50

Dapsone is use in combination with...........

28 / 50

Functional group present in INH

29 / 50

Name the drug containing pyrazine ring.........

30 / 50

DDS stands for......

31 / 50

Saturated hydrocarbons are otherwise referred as............................

32 / 50

Sulfonamides are mainly used in treatment of eye infection is

33 / 50

Given the following are long acting sulphonamides except.

34 / 50

Storage condition for Rifampicin is...............

35 / 50

Extra intestinal infections include

36 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

37 / 50

Mechanism of sulfonamides antibacterial effect is

38 / 50

Vitamin B6 is administered along with INH to avoid....................

39 / 50

Which of the given is not ant amoebic drug

40 / 50

Transmission of amoebiasis occur through_________

41 / 50

Which of the following drug belongs to 1st line

42 / 50

Excystation is _______

43 / 50

Which of the following is commonly used in treatment of acne

44 / 50

Triple bond with two carbon atoms on either side is called_______

45 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

46 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

47 / 50

Which of the following is an active agent in antiseptic.

48 / 50

Antiseptic have lower bacterial resistance

49 / 50

Amobiasis is also known as.........................

50 / 50

Leprosy is also known as.........

Your score is

The average score is 23%

0%

2697
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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

In the bioassay the conviction activity in mice is observed during……………use.

2 / 50

All of the following may enhance the action of sulfonylureas except

3 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

4 / 50

Tolbutamide is contraindicated in

5 / 50

Drug having high affinity but low intrinsic activity is called

6 / 50

Beta agonist used in bronchial asthma exert action by

7 / 50

Which of the following receptor shows the slowest response?

8 / 50

Muscarinic receptor M4 are mainly located at

9 / 50

Neostigmine may cause all of the following except

10 / 50

Most of the drug is absorbed through

11 / 50

Sweating is inhibited by

12 / 50

Action of D-tubocurarine is

13 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

14 / 50

In urinary incontinence following drug is widely used:

15 / 50

All of the following statement related to neostigmine are correct except

16 / 50

Morphine affects the eyes by:

17 / 50

Bioassays are carried out to:

18 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

19 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

20 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

21 / 50

In belladonna poisoning convulsions can be controlled by

22 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

23 / 50

Spironolactone is a prodrug and its active metabolite is

24 / 50

………………drug having highest volume of distribution.

25 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

26 / 50

Local anesthetics produce:

27 / 50

Major adverse effect of clonidine is

28 / 50

Ganglionic blocking agent may cause all of the following except

29 / 50

Hormones that increase cyclic AMP in the larger organ include all except

30 / 50

Which of the following is CYP450 enzyme inhibitor?

31 / 50

Darifenacin is a

32 / 50

Most common Phase -2nd reaction is

33 / 50

Undesirable effects of oral contraceptives include all except

34 / 50

Isolated rabbit jejunum is used

35 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

36 / 50

Pilocarpine is classified as

37 / 50

Mechanism of action of organic phosphate parathion is

38 / 50

Antidote of organo phosphorus poisoning is

39 / 50

Serious unwanted effect of epinephrine is

40 / 50

Drug of choice in motion sickness is

41 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

42 / 50

Alcuronium is a semisynthetic derivative with similar properties of

43 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

44 / 50

Drug of choice in the treatment of cardiogenic shock is

45 / 50

Atropine blocks the muscarinic actions of acetylcholine by

46 / 50

Epinephrine is added to local anaesthetics

47 / 50

Phentolamine is competitive antagonism of

48 / 50

Which of the following a is directly acting sympathomimetic agent?

49 / 50

Antidote of atropine is

50 / 50

Atropine over Dosage may cause all of the following except

Your score is

The average score is 30%

0%

1757

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

1. Nominated or elected members in "State Pharmacy Council" hold office for a term of

2 / 25

2. "Schedule F3" is related with

3 / 25

3. How many members are elected among themselves by registered Pharmacist of state

4 / 25

4. One of the following forms is needed for the cosmetic manufacture.

5 / 25

5. Manufacturing and analytical records of cosmetics are included in which schedule?

6 / 25

6. Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

7 / 25

7. Blood Bank comes under the schedule

8 / 25

8. Names of drugs which shall be marketed under generic names only come under

9 / 25

9. Private testing laboratory for carrying out tests on drugs requires.

10 / 25

10. Insulin injection according to Schedule P is should be stored

11 / 25

11. Form 20 states that

12 / 25

12. "Ampicillin capsule should be used within 24 months." This statement comes under

13 / 25

13. Pharmacy Act is established in

14 / 25

14. Appendix II is about

15 / 25

15. In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

16 / 25

16. Spurious drug comes under

17 / 25

17. Standard for disinfectant fluids come under.

18 / 25

18. Which pharmaceutical product is not included in Schedule C?

19 / 25

19. If the drug contains in filthy, putrid or decomposed substance then is known as

20 / 25

20. Insulin comes under

21 / 25

21. Crocin is sale under

22 / 25

22. Pharmacy council of India has ______ state government nominated member(s)

23 / 25

23. In AICTE the chairman is appointed by

24 / 25

24. Pharmacy Council of India is doing all of below func tions except

25 / 25

25. Schedule M, states that

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The average score is 39%

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Pharmacology MCQs for DPEE and GPAT

1 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

2 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

3 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

4 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

5 / 51

An agonist is a substance that:

6 / 51

Pharmacokinetics is:

 

7 / 51

Local anesthetics produce:

8 / 51

The group of nicotinic receptor-blocking drugs consists of:

9 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

10 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

11 / 51

Most local anesthetic agents consist of:

12 / 51

Pharmacodynamics involves the study of following?

13 / 51

Indicate the location of M2 cholinoreceptor type:

14 / 51

Pharmacodynamics involves the following?

15 / 51

Muscarinic receptors are located in:

16 / 51

M3 receptor subtype is located:

17 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

18 / 51

An antagonist is a substance that:

19 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

20 / 51

The mechanism of atropine action is:

21 / 51

What does “pharmacokinetics” include?

22 / 51

The main mechanism of most drugs absorption in GI tract is:

23 / 51

What does “affinity” mean?

24 / 51

What is implied by «active transport»?

25 / 51

Target proteins which a drug molecule binds are:

26 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

27 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

28 / 51

Pharmacodynamics involves the study of following EXCEPT:

29 / 51

Indicate a muscarinic receptor-blocking drug:

30 / 51

A good local anesthetic agent shouldn’t cause:

31 / 51

What does the term “bioavailability” mean?

32 / 51

Which of the following agents is a ganglion-blocking drug?

33 / 51

Pick out the answer which is the most appropriate to the term “receptor”

34 / 51

What does “pharmacokinetics” include?

35 / 51

Characteristics of carbachol include all of the following EXCEPT:

36 / 51

Ionizable group is responsible for:

37 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

38 / 51

Acetylcholine is not a specific neurotransmitter at:

39 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

40 / 51

What kind of substances can’t permeate membranes by passive diffusion?

41 / 51

What does “pharmacokinetics” include?

42 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

43 / 51

Parasympathomimetic drugs cause:

44 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

45 / 51

The reasons determing bioavailability are:

46 / 51

Acetylcholine is not used in clinical practice because:

47 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

48 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

49 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

50 / 51

A hydrophilic medicinal agent has the following property:

51 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

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