GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
2087
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GPAT Mock Test-2024

1 / 100

In which of the following techniques, the sample is kept below triple point?

2 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

3 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

4 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

5 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

6 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

7 / 100

X-ray crystallographic analysis of an optically active compound determines its

8 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

9 / 100

Ethambutol molecule has

10 / 100

Alkaloids are not precipitated by

11 / 100

In thiazides, following substituent is essential for diuretic activity:

12 / 100

Drugs following one compartment open model pharmacokinetics eliminate

13 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

14 / 100

Digitalis toxicity is enhanced by co-administration of

15 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

16 / 100

At physiological pH, the following compound would be mostly in the

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17 / 100

Which one of the following statements is wrong?

18 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

19 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

20 / 100

Ganciclovir is mainly used for the treatment of infection caused by

21 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

22 / 100

Anisocytic stomata are present in

23 / 100

An isosteric replacement for carboxylic acid group is

24 / 100

Which one of the following is a plasminogen activator?

25 / 100

Bacopa monnieri plant belongs to the family

26 / 100

For glyburide, all of the following metabolic reactions are logical except:

27 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

28 / 100

Artemisinin contains the following group in its structure:

29 / 100

The temperature condition for storage of drug products under cold temperature is given as

30 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

31 / 100

Nicotinic action of acetylcholine is blocked by the drug

32 / 100

Triterpenoids are active constituents of

33 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

34 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

35 / 100

Cyclophosphamide as anticancer agent acts as

36 / 100

Identify the one rational combination which has clinical benefit:

37 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

38 / 100

The healing agent used in hand creams is

39 / 100

The chemical behaviour of morphine alkaloid is

40 / 100

The given antibiotic is an example of ansamycins:

41 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

42 / 100

An example of N-glycoside is

43 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

44 / 100

Eugenol is present in

45 / 100

The ability of human eye using illuminated area to detect a particle is limited to

46 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

47 / 100

Tropane alkaloids are not present in

48 / 100

Which one of the following statements is wrong?

49 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

50 / 100

Rabies vaccine (living) is prepared using

51 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

52 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

53 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

54 / 100

Choose the right combination:

55 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

56 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

57 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

58 / 100

The characteristic of non-linear pharmacokinetics includes:

59 / 100

Selective serotonin reuptake inhibitor is

60 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

61 / 100

Oxidative phosphorylation involves

62 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

63 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

64 / 100

Humectants added in cosmetic preparations generally act by

65 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

66 / 100

Quassia wood is adulterated with

67 / 100

Aliskiren acts by

68 / 100

Which one of the following drugs is not a typical antipsychotic agent?

69 / 100

The role of borax in cold creams is

70 / 100

Class 100 area is referred to

71 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

72 / 100

Drugs in suspensions and semi-solid formulations always degrade by

73 / 100

Measurement of inulin renal clearance is a measure for

74 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

75 / 100

The applicability of Noyes-Whitney equation is to describe

76 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

77 / 100

The following protein/polypeptide has a quaternary structure:

78 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

79 / 100

Aminotransferases usually requires the following for their activity:

80 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

81 / 100

Geriatric population should be included in the following phase of clinical trials:

82 / 100

The amount of barbaloin present in Aloe vera is

83 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

84 / 100

Guggul lipids are obtained from

85 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

86 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

87 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

88 / 100

Coulter counter is used in determination of

89 / 100

In nail polish, the following polymer is used as a film-former:

90 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

91 / 100

Gingkgo biloba is used for its

92 / 100

One of the following statements is not true:

93 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

94 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

95 / 100

Sildenafil is used for treatment of one of the following
disorders:

96 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

97 / 100

Amitryptyline is synthesized from the following starting material:

98 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

99 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

100 / 100

Which of the following non-opioid analgesics is a prodrug?

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Which of the following drug belongs to 1st line

2 / 50

IUPAC name of Dapsone is .......................

3 / 50

Mechanism of sulfonamides antibacterial effect is

4 / 50

Disinfectants are _______

5 / 50

The heterocyclic nucleus present in sulphadiazine is

6 / 50

Which of the following is not susceptible to alcohol compounds.

7 / 50

Extra intestinal infections include

8 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

9 / 50

Antiseptic have lower bacterial resistance

10 / 50

Protozoan parasite responsible for amebiasis is ________

11 / 50

DDS stands for......

12 / 50

Select an anti-leprotic drug among the given...........

13 / 50

Dienes are the name given to compounds with_______

14 / 50

Which of the given is not ant amoebic drug

15 / 50

Triple bond with two carbon atoms on either side is called_______

16 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

17 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

18 / 50

Excystation is _______

19 / 50

Dapsone is use in combination with...........

20 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

21 / 50

Storage condition for Rifampicin is...............

22 / 50

Major side effects of INH.....

23 / 50

IUPAC name of INH is ...

24 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

25 / 50

Name the drug containing pyrazine ring.........

26 / 50

Sulfonamides are mainly used in treatment of eye infection is

27 / 50

Which of the following metal ion shows antimicrobial action.

28 / 50

Transmission of amoebiasis occur through_________

29 / 50

Name of drug containing dianilino group........

30 / 50

Which of the following is commonly used in treatment of acne

31 / 50

Septran is a trade name for

32 / 50

Which of these anti-tubercular drugs are also active against leprosy

33 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

34 / 50

The C=C bond in the chain of the compound considered is shown by________

35 / 50

Antiseptic are

36 / 50

Heterocyclic ring present in INH...................

37 / 50

Leprosy is also known as.........

38 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

39 / 50

Functional group present in INH

40 / 50

Which of the following drug belongs to sulfone group

41 / 50

Which of the following is an active agent in antiseptic.

42 / 50

Given the following are long acting sulphonamides except.

43 / 50

Amobiasis is also known as.........................

44 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

45 / 50

The substituent groups that are commonly associated with benzene are______

46 / 50

Functional group present in dapsone is ............

47 / 50

Sulfonamides are....................... in action.

48 / 50

Saturated hydrocarbons are otherwise referred as............................

49 / 50

Mechanism by which the antiseptic shows their action

50 / 50

Vitamin B6 is administered along with INH to avoid....................

Your score is

The average score is 23%

0%

2593
Created by 05fe696f3a90485f423c585006cddec739726cdca3e2b834e4fe849c56c710f8?s=32&d=mm&r=g | Noteskarts, D.Pharma Notes PDF, D.Pharma 1st year Notes, Pharmacy Notes Noteskarts GPAT Mock Test 2023Noteskarts

Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Local anesthetics produce:

2 / 50

Beta agonist used in bronchial asthma exert action by

3 / 50

Which of the following a is directly acting sympathomimetic agent?

4 / 50

All of the following may enhance the action of sulfonylureas except

5 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

6 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

7 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

8 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

9 / 50

Sweating is inhibited by

10 / 50

Atropine over Dosage may cause all of the following except

11 / 50

Phentolamine is competitive antagonism of

12 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

13 / 50

Isolated rabbit jejunum is used

14 / 50

Morphine affects the eyes by:

15 / 50

Neostigmine may cause all of the following except

16 / 50

Hormones that increase cyclic AMP in the larger organ include all except

17 / 50

In the bioassay the conviction activity in mice is observed during……………use.

18 / 50

All of the following statement related to neostigmine are correct except

19 / 50

Drug of choice in motion sickness is

20 / 50

Tolbutamide is contraindicated in

21 / 50

Bioassays are carried out to:

22 / 50

Antidote of organo phosphorus poisoning is

23 / 50

Alcuronium is a semisynthetic derivative with similar properties of

24 / 50

Serious unwanted effect of epinephrine is

25 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

26 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

27 / 50

Most of the drug is absorbed through

28 / 50

Antidote of atropine is

29 / 50

Epinephrine is added to local anaesthetics

30 / 50

Darifenacin is a

31 / 50

Which of the following is CYP450 enzyme inhibitor?

32 / 50

Atropine blocks the muscarinic actions of acetylcholine by

33 / 50

In urinary incontinence following drug is widely used:

34 / 50

Muscarinic receptor M4 are mainly located at

35 / 50

Drug having high affinity but low intrinsic activity is called

36 / 50

Ganglionic blocking agent may cause all of the following except

37 / 50

Most common Phase -2nd reaction is

38 / 50

Spironolactone is a prodrug and its active metabolite is

39 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

40 / 50

In belladonna poisoning convulsions can be controlled by

41 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

42 / 50

Undesirable effects of oral contraceptives include all except

43 / 50

………………drug having highest volume of distribution.

44 / 50

Which of the following receptor shows the slowest response?

45 / 50

Mechanism of action of organic phosphate parathion is

46 / 50

Drug of choice in the treatment of cardiogenic shock is

47 / 50

Major adverse effect of clonidine is

48 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

49 / 50

Pilocarpine is classified as

50 / 50

Action of D-tubocurarine is

Your score is

The average score is 30%

0%

1727

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

1. Crocin is sale under

2 / 25

2. Blood Bank comes under the schedule

3 / 25

3. Insulin injection according to Schedule P is should be stored

4 / 25

4. Pharmacy Act is established in

5 / 25

5. Pharmacy Council of India is doing all of below func tions except

6 / 25

6. Manufacturing and analytical records of cosmetics are included in which schedule?

7 / 25

7. In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

8 / 25

8. Form 20 states that

9 / 25

9. "Ampicillin capsule should be used within 24 months." This statement comes under

10 / 25

10. Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

11 / 25

11. Insulin comes under

12 / 25

12. If the drug contains in filthy, putrid or decomposed substance then is known as

13 / 25

13. Names of drugs which shall be marketed under generic names only come under

14 / 25

14. One of the following forms is needed for the cosmetic manufacture.

15 / 25

15. Spurious drug comes under

16 / 25

16. In AICTE the chairman is appointed by

17 / 25

17. Which pharmaceutical product is not included in Schedule C?

18 / 25

18. Schedule M, states that

19 / 25

19. "Schedule F3" is related with

20 / 25

20. Appendix II is about

21 / 25

21. Standard for disinfectant fluids come under.

22 / 25

22. How many members are elected among themselves by registered Pharmacist of state

23 / 25

23. Pharmacy council of India has ______ state government nominated member(s)

24 / 25

24. Nominated or elected members in "State Pharmacy Council" hold office for a term of

25 / 25

25. Private testing laboratory for carrying out tests on drugs requires.

Your score is

The average score is 39%

0%

577
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Pharmacology MCQs for DPEE and GPAT

1 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

2 / 51

Indicate the location of M2 cholinoreceptor type:

3 / 51

The group of nicotinic receptor-blocking drugs consists of:

4 / 51

Local anesthetics produce:

5 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

6 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

7 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

8 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

9 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

10 / 51

What kind of substances can’t permeate membranes by passive diffusion?

11 / 51

Most local anesthetic agents consist of:

12 / 51

Muscarinic receptors are located in:

13 / 51

Which of the following agents is a ganglion-blocking drug?

14 / 51

A hydrophilic medicinal agent has the following property:

15 / 51

The mechanism of atropine action is:

16 / 51

A good local anesthetic agent shouldn’t cause:

17 / 51

The main mechanism of most drugs absorption in GI tract is:

18 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

19 / 51

What does “pharmacokinetics” include?

20 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

21 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

22 / 51

The reasons determing bioavailability are:

23 / 51

Pharmacokinetics is:

 

24 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

25 / 51

What does “pharmacokinetics” include?

26 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

27 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

28 / 51

What is implied by «active transport»?

29 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

30 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

31 / 51

An antagonist is a substance that:

32 / 51

Pick out the answer which is the most appropriate to the term “receptor”

33 / 51

Pharmacodynamics involves the following?

34 / 51

What does the term “bioavailability” mean?

35 / 51

M3 receptor subtype is located:

36 / 51

Ionizable group is responsible for:

37 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

38 / 51

Indicate a muscarinic receptor-blocking drug:

39 / 51

Parasympathomimetic drugs cause:

40 / 51

Target proteins which a drug molecule binds are:

41 / 51

What does “pharmacokinetics” include?

42 / 51

What does “affinity” mean?

43 / 51

Acetylcholine is not used in clinical practice because:

44 / 51

Acetylcholine is not a specific neurotransmitter at:

45 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

46 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

47 / 51

An agonist is a substance that:

48 / 51

Characteristics of carbachol include all of the following EXCEPT:

49 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

50 / 51

Pharmacodynamics involves the study of following EXCEPT:

51 / 51

Pharmacodynamics involves the study of following?

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The average score is 24%

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