Introduction to biochemistry

Brief chemistry and role of proteins, polypeptides and amino acids,
classification, Qualitative tests, Biological value, Deficiency diseases.

Carbohydrates

Brief chemistry and role of carbohydrates, classification, qualitative tests, Diseases
related to carbohydrate metabolism.

Lipids

Brief chemistry and role of lipids, classification and qualitative tests. Diseases related to lipids
metabolism

Vitamins

Brief chemistry and role of vitamins and coenzymes. Role of minerals and water in life
processes.

SYLLABUS

BIOCHEMISTRY & CLINICAL PATHOLOGY

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Chapter-1

Introduction to biochemistry: Scope of biochemistry inpharmacy; Cell and its biochemical organization

Chapter-2

Carbohydrates

  • Definition, classification with examples, chemical properties
  • Monosaccharides – Structure of glucose, fructose and galactose
  • Disaccharides – structure of maltose, lactose and sucrose
  • Polysaccharides – chemical nature of starch and glycogen
  • Qualitative tests and biological role of carbohydrates 

Chapter-3

Proteins

  • Definition, classification of proteins based on composition and solubility with examples
  • Definition, classification of amino acids based on chemical nature and nutritional requirements with examples
  •  Structure of proteins (four levels of organization of protein structure)
  • Qualitative tests and biological role of proteins and amino acids
  • Diseases related to malnutrition of proteins.

Chapter-4

Lipids

  • Definition, classification with examples
  • Structure and properties of triglycerides (oils and fats)
  • Fatty acid classification – Based on chemical and nutritional requirements with examples
  • Structure and functions of cholesterol in the body
  • Lipoproteins – types, composition and functions in the body
  • Qualitative tests and functions of lipids

Chapter-5

Nucleic acids

  • Definition, purine and pyrimidine bases
  • Components of nucleosides and nucleotides with
    examples
  • Structure of DNA (Watson and Crick model), RNA
    and their functions

Chapter-6

Enzymes

  • Definition, properties and IUB and MB classification
  • Factors affecting enzyme activity
  • Mechanism of action of enzymes, Enzyme inhibitors
  • Therapeutic and pharmaceutical importance of enzymes

Chapter-7

Vitamins

  • Definition and classification with examples
  • Sources, chemical nature, functions, coenzyme form, recommended dietary requirements, deficiency diseases of fat-and water-soluble vitamins