Cyclophosphamide as anticancer agent acts as

Tropane alkaloids are not present in

Many xenobiotics are oxidized by cytochrome P450 in order to

The applicability of Noyes-Whitney equation is to describe

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

Sildenafil is used for treatment of one of the following
disorders:

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

Class 100 area is referred to

Indicate the HPLC detector that is most sensitive to change in temperature:

Which of the following non-opioid analgesics is a prodrug?

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

In which of the following techniques, the sample is kept below triple point?

The chemical behaviour of morphine alkaloid is

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

Digitalis toxicity is enhanced by co-administration of

Myasthenia gravis is diagnosed with improved neuromuscular function by using

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

Measurement of inulin renal clearance is a measure for

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

Which one of the following statements is wrong?

In thiazides, following substituent is essential for diuretic activity:

Alkaloids are not precipitated by

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

For glyburide, all of the following metabolic reactions are logical except:

An isosteric replacement for carboxylic acid group is

Bacopa monnieri plant belongs to the family

Aminotransferases usually requires the following for their activity:

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

The following protein/polypeptide has a quaternary structure:

Triterpenoids are active constituents of

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

An example of N-glycoside is

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

Drugs following one compartment open model pharmacokinetics eliminate

The ability of human eye using illuminated area to detect a particle is limited to

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

Streptomycin cannot be given orally for treatment of tuberculosis because

Artemisinin contains the following group in its structure:

At physiological pH, the following compound would be mostly in the

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

Nicotinic action of acetylcholine is blocked by the drug

Amitryptyline is synthesized from the following starting material:

Guggul lipids are obtained from

Choose the right combination:

Anisocytic stomata are present in

The amount of barbaloin present in Aloe vera is

In nail polish, the following polymer is used as a film-former:

Which one of the following is not an ex-officio member of Pharmacy Council of India?

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

Aliskiren acts by

Quassia wood is adulterated with

One of the following statements is not true:

The rate limiting step in cholesterol biosynthesis is one of the following:

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

Which one of the following statements is wrong?

Identify the one rational combination which has clinical benefit:

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

Oxidative phosphorylation involves

The characteristic of non-linear pharmacokinetics includes:

Which one of the following is a flocculating agent for a negatively charged drug?

The healing agent used in hand creams is

Coulter counter is used in determination of

Rabies vaccine (living) is prepared using

Which one of the following is a plasminogen activator?

Humectants added in cosmetic preparations generally act by

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

One mg of Lycopodium spores used in quantitative microscopy contains an average of

X-ray crystallographic analysis of an optically active compound determines its

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

In the mixing of thymol and menthol, the following type of incompatibility occurs:

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

The given antibiotic is an example of ansamycins:

Geriatric population should be included in the following phase of clinical trials:

Ganciclovir is mainly used for the treatment of infection caused by

Purity of water can be assessed by determining one of its following properties instrumentally:

Eugenol is present in

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

Drugs in suspensions and semi-solid formulations always degrade by

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

Gingkgo biloba is used for its

Which one of the following drugs is not a typical antipsychotic agent?

Which one of the following drugs does not act through G-Protein coupled receptors?

Ethambutol molecule has

The role of borax in cold creams is

The temperature condition for storage of drug products under cold temperature is given as

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

Selective serotonin reuptake inhibitor is

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?