GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test-2024

1 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

2 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

3 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

4 / 100

Aliskiren acts by

5 / 100

Class 100 area is referred to

6 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

7 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

8 / 100

Artemisinin contains the following group in its structure:

9 / 100

The amount of barbaloin present in Aloe vera is

10 / 100

Tropane alkaloids are not present in

11 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

12 / 100

Identify the one rational combination which has clinical benefit:

13 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

14 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

15 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

16 / 100

Gingkgo biloba is used for its

17 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

18 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

19 / 100

Which one of the following drugs is not a typical antipsychotic agent?

20 / 100

One of the following statements is not true:

21 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

22 / 100

The given antibiotic is an example of ansamycins:

23 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

24 / 100

Bacopa monnieri plant belongs to the family

25 / 100

Which one of the following statements is wrong?

26 / 100

The role of borax in cold creams is

27 / 100

Guggul lipids are obtained from

28 / 100

Aminotransferases usually requires the following for their activity:

29 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

30 / 100

In thiazides, following substituent is essential for diuretic activity:

31 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

32 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

33 / 100

Eugenol is present in

34 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

35 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

36 / 100

The following protein/polypeptide has a quaternary structure:

37 / 100

Humectants added in cosmetic preparations generally act by

38 / 100

The applicability of Noyes-Whitney equation is to describe

39 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

40 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

41 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

42 / 100

Alkaloids are not precipitated by

43 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

44 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

45 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

46 / 100

Geriatric population should be included in the following phase of clinical trials:

47 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

48 / 100

Selective serotonin reuptake inhibitor is

49 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

50 / 100

In which of the following techniques, the sample is kept below triple point?

51 / 100

Ganciclovir is mainly used for the treatment of infection caused by

52 / 100

The ability of human eye using illuminated area to detect a particle is limited to

53 / 100

An example of N-glycoside is

54 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

55 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

56 / 100

Anisocytic stomata are present in

57 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

58 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

59 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

60 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

61 / 100

Measurement of inulin renal clearance is a measure for

62 / 100

Which one of the following statements is wrong?

63 / 100

The chemical behaviour of morphine alkaloid is

64 / 100

Digitalis toxicity is enhanced by co-administration of

65 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

66 / 100

The characteristic of non-linear pharmacokinetics includes:

67 / 100

Coulter counter is used in determination of

68 / 100

Rabies vaccine (living) is prepared using

69 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

70 / 100

Choose the right combination:

71 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

72 / 100

Nicotinic action of acetylcholine is blocked by the drug

73 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

74 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

75 / 100

Sildenafil is used for treatment of one of the following
disorders:

76 / 100

Which one of the following is a plasminogen activator?

77 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

78 / 100

In nail polish, the following polymer is used as a film-former:

79 / 100

Triterpenoids are active constituents of

80 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

81 / 100

An isosteric replacement for carboxylic acid group is

82 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

83 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

84 / 100

Amitryptyline is synthesized from the following starting material:

85 / 100

At physiological pH, the following compound would be mostly in the

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86 / 100

Which of the following non-opioid analgesics is a prodrug?

87 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

88 / 100

The temperature condition for storage of drug products under cold temperature is given as

89 / 100

Oxidative phosphorylation involves

90 / 100

Quassia wood is adulterated with

91 / 100

The healing agent used in hand creams is

92 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

93 / 100

Drugs in suspensions and semi-solid formulations always degrade by

94 / 100

X-ray crystallographic analysis of an optically active compound determines its

95 / 100

Drugs following one compartment open model pharmacokinetics eliminate

96 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

97 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

98 / 100

Cyclophosphamide as anticancer agent acts as

99 / 100

Ethambutol molecule has

100 / 100

For glyburide, all of the following metabolic reactions are logical except:

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The average score is 20%

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Extra intestinal infections include

2 / 50

Excystation is _______

3 / 50

Disinfectants are _______

4 / 50

Which of the given is not ant amoebic drug

5 / 50

Amobiasis is also known as.........................

6 / 50

Mechanism of sulfonamides antibacterial effect is

7 / 50

Dienes are the name given to compounds with_______

8 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

9 / 50

Heterocyclic ring present in INH...................

10 / 50

IUPAC name of Dapsone is .......................

11 / 50

Functional group present in INH

12 / 50

Which of the following is an active agent in antiseptic.

13 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

14 / 50

Which of the following drug belongs to 1st line

15 / 50

Transmission of amoebiasis occur through_________

16 / 50

Major side effects of INH.....

17 / 50

Which of the following is commonly used in treatment of acne

18 / 50

Name of drug containing dianilino group........

19 / 50

The heterocyclic nucleus present in sulphadiazine is

20 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

21 / 50

The C=C bond in the chain of the compound considered is shown by________

22 / 50

Dapsone is use in combination with...........

23 / 50

Triple bond with two carbon atoms on either side is called_______

24 / 50

Which of the following is not susceptible to alcohol compounds.

25 / 50

Sulfonamides are mainly used in treatment of eye infection is

26 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

27 / 50

Saturated hydrocarbons are otherwise referred as............................

28 / 50

Vitamin B6 is administered along with INH to avoid....................

29 / 50

Antiseptic have lower bacterial resistance

30 / 50

Functional group present in dapsone is ............

31 / 50

IUPAC name of INH is ...

32 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

33 / 50

Which of these anti-tubercular drugs are also active against leprosy

34 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

35 / 50

Septran is a trade name for

36 / 50

Antiseptic are

37 / 50

DDS stands for......

38 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

39 / 50

Which of the following drug belongs to sulfone group

40 / 50

Name the drug containing pyrazine ring.........

41 / 50

Protozoan parasite responsible for amebiasis is ________

42 / 50

Leprosy is also known as.........

43 / 50

The substituent groups that are commonly associated with benzene are______

44 / 50

Given the following are long acting sulphonamides except.

45 / 50

Mechanism by which the antiseptic shows their action

46 / 50

Sulfonamides are....................... in action.

47 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

48 / 50

Which of the following metal ion shows antimicrobial action.

49 / 50

Storage condition for Rifampicin is...............

50 / 50

Select an anti-leprotic drug among the given...........

Your score is

The average score is 23%

0%

2655
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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

In belladonna poisoning convulsions can be controlled by

2 / 50

Bioassays are carried out to:

3 / 50

Spironolactone is a prodrug and its active metabolite is

4 / 50

Which of the following a is directly acting sympathomimetic agent?

5 / 50

………………drug having highest volume of distribution.

6 / 50

All of the following may enhance the action of sulfonylureas except

7 / 50

Drug having high affinity but low intrinsic activity is called

8 / 50

Drug of choice in motion sickness is

9 / 50

Atropine over Dosage may cause all of the following except

10 / 50

Local anesthetics produce:

11 / 50

Antidote of organo phosphorus poisoning is

12 / 50

Most common Phase -2nd reaction is

13 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

14 / 50

Pilocarpine is classified as

15 / 50

Muscarinic receptor M4 are mainly located at

16 / 50

Sweating is inhibited by

17 / 50

Atropine blocks the muscarinic actions of acetylcholine by

18 / 50

Undesirable effects of oral contraceptives include all except

19 / 50

Morphine affects the eyes by:

20 / 50

Neostigmine may cause all of the following except

21 / 50

Serious unwanted effect of epinephrine is

22 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

23 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

24 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

25 / 50

Mechanism of action of organic phosphate parathion is

26 / 50

Which of the following receptor shows the slowest response?

27 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

28 / 50

Major adverse effect of clonidine is

29 / 50

Most of the drug is absorbed through

30 / 50

Tolbutamide is contraindicated in

31 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

32 / 50

Ganglionic blocking agent may cause all of the following except

33 / 50

Isolated rabbit jejunum is used

34 / 50

Darifenacin is a

35 / 50

Which of the following is CYP450 enzyme inhibitor?

36 / 50

All of the following statement related to neostigmine are correct except

37 / 50

In the bioassay the conviction activity in mice is observed during……………use.

38 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

39 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

40 / 50

Phentolamine is competitive antagonism of

41 / 50

Beta agonist used in bronchial asthma exert action by

42 / 50

Epinephrine is added to local anaesthetics

43 / 50

Action of D-tubocurarine is

44 / 50

Hormones that increase cyclic AMP in the larger organ include all except

45 / 50

In urinary incontinence following drug is widely used:

46 / 50

Drug of choice in the treatment of cardiogenic shock is

47 / 50

Alcuronium is a semisynthetic derivative with similar properties of

48 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

49 / 50

Antidote of atropine is

50 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

Your score is

The average score is 30%

0%

1750

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

1. Which pharmaceutical product is not included in Schedule C?

2 / 25

2. Standard for disinfectant fluids come under.

3 / 25

3. "Schedule F3" is related with

4 / 25

4. Insulin comes under

5 / 25

5. Pharmacy council of India has ______ state government nominated member(s)

6 / 25

6. Pharmacy Act is established in

7 / 25

7. "Ampicillin capsule should be used within 24 months." This statement comes under

8 / 25

8. In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

9 / 25

9. Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

10 / 25

10. Crocin is sale under

11 / 25

11. One of the following forms is needed for the cosmetic manufacture.

12 / 25

12. Form 20 states that

13 / 25

13. Manufacturing and analytical records of cosmetics are included in which schedule?

14 / 25

14. Pharmacy Council of India is doing all of below func tions except

15 / 25

15. Nominated or elected members in "State Pharmacy Council" hold office for a term of

16 / 25

16. How many members are elected among themselves by registered Pharmacist of state

17 / 25

17. Names of drugs which shall be marketed under generic names only come under

18 / 25

18. Schedule M, states that

19 / 25

19. Spurious drug comes under

20 / 25

20. Appendix II is about

21 / 25

21. Blood Bank comes under the schedule

22 / 25

22. In AICTE the chairman is appointed by

23 / 25

23. If the drug contains in filthy, putrid or decomposed substance then is known as

24 / 25

24. Insulin injection according to Schedule P is should be stored

25 / 25

25. Private testing laboratory for carrying out tests on drugs requires.

Your score is

The average score is 39%

0%

587
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Pharmacology MCQs for DPEE and GPAT

1 / 51

Parasympathomimetic drugs cause:

2 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

3 / 51

An antagonist is a substance that:

4 / 51

Indicate a muscarinic receptor-blocking drug:

5 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

6 / 51

Most local anesthetic agents consist of:

7 / 51

The reasons determing bioavailability are:

8 / 51

An agonist is a substance that:

9 / 51

A good local anesthetic agent shouldn’t cause:

10 / 51

Target proteins which a drug molecule binds are:

11 / 51

The mechanism of atropine action is:

12 / 51

The main mechanism of most drugs absorption in GI tract is:

13 / 51

Ionizable group is responsible for:

14 / 51

M3 receptor subtype is located:

15 / 51

What does “affinity” mean?

16 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

17 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

18 / 51

What kind of substances can’t permeate membranes by passive diffusion?

19 / 51

What does the term “bioavailability” mean?

20 / 51

Pharmacodynamics involves the following?

21 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

22 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

23 / 51

A hydrophilic medicinal agent has the following property:

24 / 51

Pharmacodynamics involves the study of following?

25 / 51

What is implied by «active transport»?

26 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

27 / 51

Muscarinic receptors are located in:

28 / 51

Pick out the answer which is the most appropriate to the term “receptor”

29 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

30 / 51

Indicate the location of M2 cholinoreceptor type:

31 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

32 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

33 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

34 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

35 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

36 / 51

Acetylcholine is not a specific neurotransmitter at:

37 / 51

Acetylcholine is not used in clinical practice because:

38 / 51

The group of nicotinic receptor-blocking drugs consists of:

39 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

40 / 51

Pharmacodynamics involves the study of following EXCEPT:

41 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

42 / 51

What does “pharmacokinetics” include?

43 / 51

Local anesthetics produce:

44 / 51

What does “pharmacokinetics” include?

45 / 51

Which of the following agents is a ganglion-blocking drug?

46 / 51

What does “pharmacokinetics” include?

47 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

48 / 51

Pharmacokinetics is:

 

49 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

50 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

51 / 51

Characteristics of carbachol include all of the following EXCEPT:

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The average score is 24%

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