GPAT Quiz 2024

  • GPAT multiple choice question bank for govt. service exams. Important MCQs from GPAT Quiz, GPAT Mock Test Series, GPAT Exam 2024 MCQs, Noteskarts Test Series
  • This test is Improve for Pharmacy exam like Diploma in Pharmacy exit exam MCQs (DPEE), GPAT, & other competitive exam. 
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GPAT Mock Test-2024

1 / 100

Oxidative phosphorylation involves

2 / 100

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products?

3 / 100

Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in

4 / 100

Indicate the HPLC detector that is most sensitive to change in temperature:

5 / 100

Stevens Johnson syndrome is the most common adverse effect associated with one of the following category of drugs:

6 / 100

Which one of the following is a plasminogen activator?

7 / 100

The rate limiting step in cholesterol biosynthesis is one of the following:

8 / 100

One of the following statements is not true:

9 / 100

Quassia wood is adulterated with

10 / 100

Which one of the following drugs is most effective in preventing transmission of HIV virus from the mother to the foetus?

11 / 100

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 h and Vd of 5 L. The dose required in a sustained release product will be

12 / 100

The effects observed following systemic administration of levodopa in the treatment of Parkinsonism have been
attributed to its catabolism to dopamine. Carbidopa can markedly increase the proportion of levodopa that
crosses the blood-brain barrier by

13 / 100

The amount of barbaloin present in Aloe vera is

14 / 100

The given antibiotic is an example of ansamycins:

15 / 100

Aliskiren acts by

16 / 100

How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?

17 / 100

For glyburide, all of the following metabolic reactions are logical except:

18 / 100

Identify the drug which is not used in the treatment of malaria caused by Plasmodium falciparum.

19 / 100

Many xenobiotics are oxidized by cytochrome P450 in order to

20 / 100

Guggul lipids are obtained from

21 / 100

Coulter counter is used in determination of

22 / 100

Myasthenia gravis is diagnosed with improved neuromuscular function by using

23 / 100

Eugenol is present in

24 / 100

Amitryptyline is synthesized from the following starting material:

25 / 100

Selective serotonin reuptake inhibitor is

26 / 100

Which one of the following drugs is withdrawn from the market due to torsade de pointes?

27 / 100

Drugs in suspensions and semi-solid formulations always degrade by

28 / 100

In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

29 / 100

Gingkgo biloba is used for its

30 / 100

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is

31 / 100

Which one of the following is not an ex-officio member of Pharmacy Council of India?

32 / 100

The volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be

33 / 100

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin’s Lymphoma?

34 / 100

In nail polish, the following polymer is used as a film-former:

35 / 100

Triterpenoids are active constituents of

36 / 100

Which one of the following statements is wrong?

37 / 100

Which one of the following drugs is not a typical antipsychotic agent?

38 / 100

The ability of human eye using illuminated area to detect a particle is limited to

39 / 100

The applicability of Noyes-Whitney equation is to describe

40 / 100

The chemical behaviour of morphine alkaloid is

41 / 100

Digitalis toxicity is enhanced by co-administration of

42 / 100

A compound will be sensitive towards IR radiation only when one of the following properties undergo
transition on

43 / 100

Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:

44 / 100

In the mixing of thymol and menthol, the following type of incompatibility occurs:

45 / 100

Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

46 / 100

The following protein/polypeptide has a quaternary structure:

47 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

48 / 100

Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?

49 / 100

One mg of Lycopodium spores used in quantitative microscopy contains an average of

50 / 100

Bloom strength is used to check the quality of
(a) (b)
(c)  (d)

51 / 100

An isosteric replacement for carboxylic acid group is

52 / 100

The role of borax in cold creams is

53 / 100

Which one of the following is a flocculating agent for a negatively charged drug?

54 / 100

The temperature condition for storage of drug products under cold temperature is given as

55 / 100

Humectants added in cosmetic preparations generally act by

56 / 100

Which one of the following drugs does not act through G-Protein coupled receptors?

57 / 100

Ganciclovir is mainly used for the treatment of infection caused by

58 / 100

Which of the following non-opioid analgesics is a prodrug?

59 / 100

Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic
convulsions?

60 / 100

Artemisinin contains the following group in its structure:

61 / 100

In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

62 / 100

Geriatric population should be included in the following phase of clinical trials:

63 / 100

Nicotinic action of acetylcholine is blocked by the drug

64 / 100

In which of the following techniques, the sample is kept below triple point?

65 / 100

Barbiturates with substitution at the following position possess acceptable hypnotic activity:

66 / 100

Sildenafil is used for treatment of one of the following
disorders:

67 / 100

The common structural feature amongst the three
categories of anti-convulsant drugs barbiturates,
succinimides and hydantoins is
(a)  (b)
(c)  (d)

68 / 100

Ethambutol molecule has

69 / 100

Glass transition temperature is detected through
(a)
(b)
(c)
(d)

70 / 100

Chemical nomenclature of procaine is
(a)
(b)
(c)
(d)

71 / 100

What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol?

72 / 100

The healing agent used in hand creams is

73 / 100

Class 100 area is referred to

74 / 100

The characteristic of non-linear pharmacokinetics includes:

75 / 100

An example of N-glycoside is

76 / 100

Anisocytic stomata are present in

77 / 100

Identify the one rational combination which has clinical benefit:

78 / 100

Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:

79 / 100

Streptomycin cannot be given orally for treatment of tuberculosis because

80 / 100

In thiazides, following substituent is essential for diuretic activity:

81 / 100

Highly branched three dimensional macromolecules with controlled structures with all bonds originating from a central core are known as

82 / 100

Purity of water can be assessed by determining one of its following properties instrumentally:

83 / 100

In the TCA cycle, at which of the following enzyme-catalysed steps, incorporation of elements of water into an intermediate of the cycle takes place?

84 / 100

In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is

85 / 100

Rabies vaccine (living) is prepared using

86 / 100

X-ray crystallographic analysis of an optically active compound determines its

87 / 100

Cyclophosphamide as anticancer agent acts as

88 / 100

At physiological pH, the following compound would be mostly in the

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89 / 100

Aminotransferases usually requires the following for their activity:

90 / 100

Bacopa monnieri plant belongs to the family

91 / 100

Drugs following one compartment open model pharmacokinetics eliminate

92 / 100

Choose the right combination:

93 / 100

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram h/mL, respectively. The absolute availability of the drug through oral administration is

94 / 100

Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C.

95 / 100

Tropane alkaloids are not present in

96 / 100

Alkaloids are not precipitated by

97 / 100

Thioglycolic acid-like compounds have applications in following type of cosmetic formulations:

98 / 100

Which one of the following statements is wrong?

99 / 100

Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with chronic myeloid Leukemia?

100 / 100

Measurement of inulin renal clearance is a measure for

Your score is

The average score is 20%

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Pharmaceutical Chemistry Section A

In this MCQs test 50 questions and 30 min for solve all question Noteskarts Test Series

1 / 50

Excystation is _______

2 / 50

The substituent groups that are commonly associated with benzene are______

3 / 50

Antiseptic have lower bacterial resistance

4 / 50

Which of the following is an active agent in antiseptic.

5 / 50

Major side effects of INH.....

6 / 50

4-amino-N-(diaminomethylidene) benzenesulfonamide is the IUPAC name of

7 / 50

Functional group present in INH

8 / 50

DDS stands for......

9 / 50

In which among the following alkane, a carbon atom is displayed so as to form a compactly structure with the resemblance of a butterfly wing?

10 / 50

Mechanism by which the antiseptic shows their action

11 / 50

Select an anti-leprotic drug among the given...........

12 / 50

Septran is a trade name for

13 / 50

Which of the following drug belongs to 1st line

14 / 50

Functional group present in dapsone is ............

15 / 50

Storage condition for Rifampicin is...............

16 / 50

N-[(4-amino phenyl) sulfonyl] acetamide the IUPAC name of

17 / 50

Vitamin B6 is administered along with INH to avoid....................

18 / 50

The destruction of all micro organism on inanimate objects or surfaces is known as

19 / 50

Dienes are the name given to compounds with_______

20 / 50

Sulfonamides are....................... in action.

21 / 50

Which of the following drug belongs to sulfone group

22 / 50

Heterocyclic ring present in INH...................

23 / 50

Extra intestinal infections include

24 / 50

The substituent in the chain is named by replacing the "ane" in the alkanes by________.

25 / 50

Protozoan parasite responsible for amebiasis is ________

26 / 50

Mechanism of sulfonamides antibacterial effect is

27 / 50

Transmission of amoebiasis occur through_________

28 / 50

Given the following are long acting sulphonamides except.

29 / 50

Which of the following is used as an antimicrobial cleanser to clean the skin site before surgery.

30 / 50

The first step in IUPAC namenclatute is to identify the total number of carbon atoms present in the compound.

31 / 50

Name of drug containing dianilino group........

32 / 50

Which of the following is not susceptible to alcohol compounds.

33 / 50

Leprosy is also known as.........

34 / 50

The heterocyclic nucleus present in sulphadiazine is

35 / 50

Amobiasis is also known as.........................

36 / 50

Identify the correct alkane name for the molecular formula C30H62 . 

37 / 50

Triple bond with two carbon atoms on either side is called_______

38 / 50

Name the drug containing pyrazine ring.........

39 / 50

Antiseptic are

40 / 50

IUPAC name of INH is ...

41 / 50

Which of the following metal ion shows antimicrobial action.

42 / 50

Saturated hydrocarbons are otherwise referred as............................

43 / 50

Which of the given is not ant amoebic drug

44 / 50

Which of the following is commonly used in treatment of acne

45 / 50

Disinfectants are _______

46 / 50

The C=C bond in the chain of the compound considered is shown by________

47 / 50

Which of these anti-tubercular drugs are also active against leprosy

48 / 50

Sulfonamides are mainly used in treatment of eye infection is

49 / 50

IUPAC name of Dapsone is .......................

50 / 50

Dapsone is use in combination with...........

Your score is

The average score is 23%

0%

2744
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Pharmacology & Toxicology MCQs for DPEE | D.Pharma Exit Exam Most Important Question 2022-23

1 / 50

Most common Phase -2nd reaction is

2 / 50

Neostigmine may cause all of the following except

3 / 50

Darifenacin is a

4 / 50

Antidote of atropine is

5 / 50

Hormones that increase cyclic AMP in the larger organ include all except

6 / 50

Drug of choice in motion sickness is

7 / 50

Mechanism of action of organic phosphate parathion is

8 / 50

Alcuronium is a semisynthetic derivative with similar properties of

9 / 50

Tolbutamide is contraindicated in

10 / 50

Drug having high affinity but low intrinsic activity is called

11 / 50

Which of the following drug may cause cycloplegia when used topically in the eye?

12 / 50

Ganglionic blocking agent may cause all of the following except

13 / 50

Acetylcholine and physostigmine are examples of……………… type drug interaction.

14 / 50

Sweating is inhibited by

15 / 50

Atropine over Dosage may cause all of the following except

16 / 50

Drug of the following drugs. Does not cross the blood-brain barrier?

17 / 50

Activation of alpha-2 receptors in the pancreatic islets causes

18 / 50

Spironolactone is a prodrug and its active metabolite is

19 / 50

Bioassays are carried out to:

20 / 50

Most of the drug is absorbed through

21 / 50

Pilocarpine is classified as

22 / 50

In the treatment of myasthenia gravis, the best agent for distinguishing between myashenic crisis and cholinergic crisis, given intravenously is

23 / 50

Undesirable effects of oral contraceptives include all except

24 / 50

Drug of choice in the treatment of cardiogenic shock is

25 / 50

Epinephrine is added to local anaesthetics

26 / 50

Following are the chloride channel blocker
(P) Amiloride (Q) Cadmium
(R) Picrotoxin. (S) Ketamine

27 / 50

Muscarinic receptor M4 are mainly located at

28 / 50

Antidote of organo phosphorus poisoning is

29 / 50

Action of D-tubocurarine is

30 / 50

All of the following statement related to neostigmine are correct except

31 / 50

Local anesthetics produce:

32 / 50

Which of the following agent irreversibly bound with acetyl cholinesterase.

33 / 50

In belladonna poisoning convulsions can be controlled by

34 / 50

Atropine blocks the muscarinic actions of acetylcholine by

35 / 50

In the bioassay the conviction activity in mice is observed during……………use.

36 / 50

………………drug having highest volume of distribution.

37 / 50

Morphine affects the eyes by:

38 / 50

All of the following may enhance the action of sulfonylureas except

39 / 50

Phentolamine is competitive antagonism of

40 / 50

Most serious adverse effect of antithyroid drug, propylthiouracil is

41 / 50

Which of the following a is directly acting sympathomimetic agent?

42 / 50

In urinary incontinence following drug is widely used:

43 / 50

Major adverse effect of clonidine is

44 / 50

Which of the following receptor shows the slowest response?

45 / 50

Neostigmine effectively antagonizes skeletal muscle relaxation produced by

46 / 50

Isolated rabbit jejunum is used

47 / 50

Serious unwanted effect of epinephrine is

48 / 50

Beta agonist used in bronchial asthma exert action by

49 / 50

Which of the following is CYP450 enzyme inhibitor?

50 / 50

Atropine is used prior the administration of a general Anesthetics agent due to become it

Your score is

The average score is 30%

0%

1769

Pharmacy Law & Ethics Quiz | MCQs

1 / 25

Blood Bank comes under the schedule

2 / 25

Names of drugs which shall be marketed under generic names only come under

3 / 25

Form 20 states that

4 / 25

Schedule M, states that

5 / 25

Standard for disinfectant fluids come under.

6 / 25

Manufacturing and analytical records of cosmetics are included in which schedule?

7 / 25

Appendix II is about

8 / 25

How many members are elected among themselves by registered Pharmacist of state

9 / 25

In AICTE the chairman is appointed by

10 / 25

Insulin injection according to Schedule P is should be stored

11 / 25

"Ampicillin capsule should be used within 24 months." This statement comes under

12 / 25

If the drug contains in filthy, putrid or decomposed substance then is known as

13 / 25

Which pharmaceutical product is not included in Schedule C?

14 / 25

In the "Joint State Pharmacy Council" elected member(s) among the Registered Pharmacists is/are

15 / 25

Insulin comes under

16 / 25

Crocin is sale under

17 / 25

Application for grant of a licence to manufacture Ayurvedic, Sidhha or Unani drugs requires.

18 / 25

Spurious drug comes under

19 / 25

Pharmacy Act is established in

20 / 25

"Schedule F3" is related with

21 / 25

Pharmacy council of India has ______ state government nominated member(s)

22 / 25

One of the following forms is needed for the cosmetic manufacture.

23 / 25

Pharmacy Council of India is doing all of below func tions except

24 / 25

Private testing laboratory for carrying out tests on drugs requires.

25 / 25

Nominated or elected members in "State Pharmacy Council" hold office for a term of

Your score is

The average score is 40%

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605
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Pharmacology MCQs for DPEE and GPAT

1 / 51

What does the term “bioavailability” mean?

2 / 51

Indicate the local anesthetic agent, which has a shorter duration of action:

3 / 51

Target proteins which a drug molecule binds are:

4 / 51

Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?

5 / 51

If an agonist can produce submaximal effects and has moderate efficacy it’s called:

6 / 51

The mechanism of atropine action is:

7 / 51

If an agonist can produce maximal effects and has high efficacy it’s called:

8 / 51

What does “pharmacokinetics” include?

9 / 51

Indicate a cholinomimetic agent, which is related to direct-acting drugs:

10 / 51

Pick out the answer which is the most appropriate to the term “receptor”

11 / 51

Pharmacodynamics involves the study of following?

12 / 51

The main mechanism of most drugs absorption in GI tract is:

13 / 51

Most local anesthetic agents consist of:

14 / 51

What kind of substances can’t permeate membranes by passive diffusion?

15 / 51

Pharmacodynamics involves the following?

16 / 51

Muscarinic receptors are located in:

17 / 51

An antagonist is a substance that:

18 / 51

What is implied by «active transport»?

19 / 51

Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

20 / 51

A good local anesthetic agent shouldn’t cause:

21 / 51

A hydrophilic medicinal agent has the following property:

22 / 51

Which of the following direct-acting cholinomimetics is mainly muscarinic in action?

23 / 51

Characteristics of carbachol include all of the following EXCEPT:

24 / 51

Indicate the skeletal muscle relaxant, which is a depolarizing agent:

25 / 51

The symptoms of mushroom poisoning include all of the following EXCEPT:

26 / 51

Which one of the following local anesthetics is an ester of benzoic acid?

27 / 51

Which of the following drugs is a nondepolarizing muscle relaxant?

28 / 51

Acetylcholine is not a specific neurotransmitter at:

29 / 51

The effect of the drug on parasympathetic function declines rapidly in all organs EXCEPT:

30 / 51

Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:

31 / 51

Indicate the drug, which is rapidly and fully distributed into CNS and has a greater effect than most other antimuscarinic
agents?

32 / 51

Which of the following drugs is both a muscarinic and nicotinic blocker?

33 / 51

Which of the following cholinomimetics activates both muscarinic and nicotinic receptors?

34 / 51

An agonist is a substance that:

35 / 51

What does “affinity” mean?

36 / 51

Ionizable group is responsible for:

37 / 51

The reasons determing bioavailability are:

38 / 51

Indicate the drug, which has greater potency of the local anesthetic action:

39 / 51

Pharmacokinetics is:

 

40 / 51

Pharmacodynamics involves the study of following EXCEPT:

41 / 51

Indicate a muscarinic receptor-blocking drug:

42 / 51

Which one of the following groups is responsible for the duration of the local anesthetic action?

43 / 51

The group of nicotinic receptor-blocking drugs consists of:

44 / 51

Which of the following agents is a ganglion-blocking drug?

45 / 51

Indicate the location of M2 cholinoreceptor type:

46 / 51

What does “pharmacokinetics” include?

47 / 51

Parasympathomimetic drugs cause:

48 / 51

Local anesthetics produce:

49 / 51

M3 receptor subtype is located:

50 / 51

Acetylcholine is not used in clinical practice because:

51 / 51

What does “pharmacokinetics” include?

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The average score is 24%

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