SYLLABUS

PHARMACOLOGY & TOXICOLOGY​

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Chapter-1

General Pharmacology

  • Introduction and scope of Pharmacology
  • Various routes of drug administration – advantages and disadvantages
  • Drug absorption – definition, types, factors affecting drug absorption
  • Bioavailability and the factors affecting bioavailability
  • Drug distribution – definition, factors affecting drug distribution
  • Biotransformation of drugs – Definition, types of biotransformation reactions, factors influencing drug metabolisms
  • Excretion of drugs – Definition, routes of drug excretion

Chapter-2

  • Drugs Acting on the Peripheral Nervous System

  • Steps involved in neurohumoral transmission

  • Definition, classification, pharmacological actions, dose, indications, and contraindications of

a) Cholinergic drugs
b) Anti-Cholinergic drugs
c) Adrenergic drugs
d) Anti-adrenergic drugs
e) Neuromuscular blocking agents
f) Drugs used in Myasthenia gravis
g) Local anaesthetic agents
h) Non-Steroidal Anti Inflammatory drugs (NSAIDs)

Chapter-3

  • Drugs Acting on the Eye
    Definition, classification, pharmacological actions, dose, indications and contraindications of

  • Miotics
  • Mydriatics
  • Drugs used in Glaucoma

Chapter-4

Drugs Acting on the Central Nervous System Definition, classification, pharmacological actions, dose, indications and contraindications of

  • General anaesthetics
  • Hypnotics and sedatives
  • Anti-Convulsant drugs
  • Anti-anxiety drugs
  • Anti-depressant drugs
  •  Anti-psychotics
  • Nootropic agents
  • Centrally acting muscle relaxants
  • Opioid analgesics

Chapter-5

Drugs Acting on the Cardiovascular System Definition, classification, pharmacological actions, dose, indications and contraindications of

  • Anti-hypertensive drugs
  • Anti-anginal drugs
  • Anti-arrhythmic drugs
  • Drugs used in atherosclerosis and Congestive heart failure

Chapter-6

Drugs Acting on Blood and Blood Forming Organs Definition, classification, pharmacological actions, dose, indications and contraindications of

  • Hematinic agents
  • Anti-coagulants
  • Anti-platelet agents
  • Thrombolytic drugs

Chapter-7

Definition, classification, pharmacological actions, dose, indications and contraindications of

  • Bronchodilators
  • Expectorants
  • Anti-tussive agents
  • Mucolytic agents

Chapter-8

Drugs Acting on the Gastro Intestinal Tract

Definition, classification, pharmacological actions, dose, indications and contraindications of

  • Anti-ulcer drugs
  • Anti-emetics
  • Laxatives and purgatives
  • Anti-diarrheal drugs

Chapter-9

Drugs Acting on the Kidney
Definition, classification, pharmacological actions, dose, indications, and contraindications of

  • Diuretics
  • Anti-Diuretics

Chapter-10

Hormones and Hormone Antagonists Physiological and pathological role and clinical uses of

  • Thyroid hormones
  • Anti-thyroid drugs
  • Parathormone
  • Calcitonin
  • Vitamin D
  • Insulin
  • Oral hypoglycemic agents
  • Estrogen
  • Progesterone
  • Oxytocin
  • Corticosteroids

Chapter-11

Autacoids

  • Physiological role of Histamine, 5 HT and Prostaglandins
  • Classification, clinical uses and adverse effects of antihistamines and 5 HT antagonists

Chapter-12

Chemotherapeutic Agents:

Introduction, basic principles of chemotherapy of infections, infestations and neoplastic diseases, Classification, dose, indication and contraindications of drugs belonging to

  • Penicillins
  • Cephalosporins
  • Aminoglycosides
  • Fluoroquinolones
  • Macrolides
  • Tetracyclines
  • Sulphonamides
  • Anti-tubercular drugs
  • Anti-fungal drugs
  • Anti-viral drugs
  • Anti-amoebic agents
  • Anthelmintics
  • Anti-malarial agents
  • Anti-neoplastic agents

Chapter-13

Biologicals

Definition, types and indications of biological agents with examples